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A simpler path to answers for patients with mast cell activation syndrome

A random urine test panel aids in diagnosing mast cell activation syndrome (MCAS), a complex condition often misdiagnosed due to overlapping symptoms. The panel improves access, speeds up diagnosis, and enables individualized treatment by detecting key mast cell mediators.

August 11, 2025
Rabbits, Chikungunya, and More Viral News: Matthew Binnicker, Ph.D.
August 28, 2025

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and Matthew Binnicker, Ph.D., a microbiologist and virologist and chief scientific officer of Mayo Clinic Laboratories, discuss recent developments in viral infections.

Elevating Clinical Lab Websites in a Changing Technology Landscape
August 25, 2025

In this episode of the “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, is joined by Travis Engelhaupt, digital experience director, and Naomi Lovell, project manager. Together, they discuss website trends and best practices.

Practical Legal Insight and Tips: Compliance Issues for Hospital Laboratory Outreach Programs
August 20, 2025

Register now – Nov. 19, 2025: Regulatory compliance and recent policy changes at the federal and state levels relevant to hospital laboratory outreach programs.

Discussion as Pedagogical Strategy
December 20, 2018

Discussion is an effective pedagogical strategy to facilitate a learning experience and assess understanding. Carrie Bowler, Program Manager of Staff Development in the Department of Laboratory Medicine and Pathology, discusses the benefits of discussion as a strategy.

Communiqué
High-Sensitivity Troponin Assay Promises Novel Uses in Managing Patients with Chronic Heart Disease
December 18, 2018

After a long wait, the U.S. Food and Drug Administration has finally approved the Elecsys Troponin T Gen 5 STAT blood test. Recently, the Beckman hscTnI assay was also approved. These high-sensitivity troponin assays will benefit emergency departments across the country because the results will allow for earlier and faster recognition of acute myocardial infarction, which interrupts the blood supply to an area of the heart.

The Right Medication for You: Pharmacogenomics Testing at Mayo Clinic
December 5, 2018

How Your Genes Determine which Medications Work Best for You The drugs available today to treat diseases are powerful agents that work as intended for[...]

They Did “WHAT?!” Capturing Patient Experience to Increase Patient Satisfaction
November 28, 2018

This “Phlebotomy” webinar will discuss how a patient’s “experience” is the entirety of all the interactions that person has had within the health care system. Each member of a health care team plays a role in enhancing patient satisfaction, which contributes to the patient experience.

Mayo Medical Laboratories Rebrands Its Name as Mayo Clinic Laboratories
November 13, 2018

Mayo Medical Laboratories, the global reference laboratory of Mayo Clinic, has changed its name to Mayo Clinic Laboratories.

Protimes, Clotting, and Fibrin–Oh My: A Reflection on Hemostasis
November 1, 2018

Reilly Hannon, a student in the Mayo Clinic Medical Laboratory Science program, reflects on her course in hemostasis.

Notification of Business Name Change to Mayo Clinic Laboratories
October 26, 2018

Effective November 9, 2018, our business name will change from Mayo Collaborative Services, LLC, doing business as (d/b/a) Mayo Medical Laboratories to Mayo Collaborative Services, LLC, d/b/a Mayo Clinic Laboratories. The change to Mayo Clinic Laboratories will more accurately reflect the benefit we are able to bring to our clients every day.

Necrotizing Autoimmune Myopathy [Test in Focus]
October 25, 2018

Necrotizing autoimmune myopathy (NAM) is a serious but rare muscle disease strongly associated with autoantibodies to either the protein signal recognition particle (SRP) or the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR). NAM typically manifests with subacute proximal limb muscle weakness and persistently elevated serum creatine kinase (CK) concentrations, but slower onsets can occur and complicate diagnosis.

Chromium and Cobalt Testing [Test in Focus]
October 19, 2018

Chromium and cobalt blood tests are used to monitor exposure to these elements. Both of these elements are naturally occurring and widely distributed in the environment. Previously, serum samples were collected and used to monitor patients with metal-on-metal implants, but serum can easily be contaminated during the harvesting and separation of the serum from the cellular blood components causing incorrect results. By using the new EDTA anticoagulated whole-blood test, which is collected in a trace element tube instead of using serum, the risk of contamination is significantly reduced.

Communiqué
Gadolinium Accumulation in Brain Tissue following Contrast-Enhanced MRI Has Not Been Shown to Have Harmful Side Effects
September 18, 2018

Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article discusses the recent discovery that small amounts of gadolinium remain in human brain tissue following intravenous administration of GBCAs.

Top Gun Phlebotomy: Pseudohyperkalemia
September 10, 2018

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., describes how pseudohyperkalemia has many causes, from collection techniques, processing, and even transport. This presentation focuses on the various preanalytic and analytic causes of pseudohyperkalemia and what you as a phlebotomist can do to prevent it.

Biologic Therapies: Reflexive Approaches to Optimizing Treatment for IBD
September 7, 2018

Many patients may have flare-ups of their disease, or they may stop responding to treatment. In these situations, the clinician may choose to increase the dose administered or recommend more frequent injections. One cause of decreased response to treatment is the appearance of anti-drug antibodies or “immunogenicity.”

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