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A Mayo Pathologist’s Journey through Paraneoplastic Syndrome and a Double Lung Transplant: Dr. Brad Karon

After mysterious neurological symptoms began in 2010, Brad Karon, M.D., Ph.D., was diagnosed with paraneoplastic syndrome, a rare condition that led to groundbreaking research and test development at Mayo Clinic. Years later, pulmonary fibrosis and a double lung transplant would test him once again — and redefine his resilience.

July 21, 2025
Toxicology Transformed: From Opioids to Saliva — A Chemistry-Centric Journey
August 1, 2025

As drug trends and diagnostic technologies evolve, toxicology must adapt to meet the demands of healthcare, workplace safety, and public health—focusing on opioid detection, CBD use, patient-centered testing, and new methods like saliva analysis, each bringing distinct challenges and opportunities. The following podcast episodes feature chemistry-related interviews that discuss these topics.

New Tools for the Changing Landscape of Tick-Borne Diseases: Elitza Theel, Ph.D.
July 31, 2025

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, for a timely discussion on tick-borne diseases.

What’s New in Quality & Regulatory? (2025)
October 14, 2025

Register now – Oct. 14, 2025 - PACE/State of FL - This webinar will provide an overview of recent regulatory changes impacting clinical laboratories. This will include the latest updates to Clinical Laboratory Improvement Amendments (CLIA) memos and brochures, the termination of Clinical Laboratory Improvement Advisory Committee (CLIAC) and its impact to clinical laboratories, a summary of the FDA LDT final rule regulatory journey, and a discussion of the shift to announced inspections.

Week in Review: November 11
November 11, 2022

Topic highlights include: Health care officials prepare as RSV, influenza cases increase in Minnesota, Health and science are on the ballot this election. Here’s what we’re watching, Proposition 209: Arizona voters back lowering maximum interest rates on medical debt

Legislation, leadership, and MayoComplete: Dr. Bill Morice
November 10, 2022

William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, joins "Answers From the Lab" for his weekly leadership update with host Bobbi Pritt, M.D., interim chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic. In this episode, Dr. Pritt and Dr. Morice discuss their new roles at Mayo Clinic and update listeners on the latest legislative news impacting the laboratory and diagnostic industries. They also highlight the launch of MayoComplete, Mayo Clinic Laboratories’ robust suite of oncology and hematology testing that uses next-generation sequencing to identify and evaluate presence of mutations.

Tropical Storm Nicole
November 9, 2022

As Tropical Storm Nicole approaches Florida, the Mayo Clinic Laboratories Florida location will close tonight, Nov. 9, at 7:30 p.m. ET, as a safety precaution. The location will remain closed through 7:30 p.m. ET tomorrow, Nov. 10.

Cross-laboratory collaboration accelerates gold-standard SRA testing
November 9, 2022

Utilizing testing capabilities of two separate laboratory facilities, Mayo Clinic Laboratories’ new serotonin release assay (SRA) is a gold-standard test supported by decades of clinical hematopathologic experience and advanced mass spectrometry testing.

Comprehensive panel boosts GIST diagnosis sensitivity
November 8, 2022

Rondell Graham, M.B.B.S., describes Mayo Clinic Laboratories' new assay for gastrointestinal stromal tumors, or GIST. The panel covers multiple mutations, to better inform diagnosis and treatment options.

Mayo Clinic Laboratory and pathology research roundup: November 8
November 8, 2022

This week's research roundup features: Evaluating the significance of pancreatobiliary fluorescence in situ hybridization polysomy on prognosis in de novo cholangiocarcinoma

Your Laboratory’s Best Kept Secret
November 8, 2022

An effective laboratory outreach program can unlock a wide array of benefits for a health system and its laboratory. Every day, hospital laboratories struggle for dollars to meet the challenges of decreasing reimbursement and rising costs. How are they expected to survive (or possibly even thrive)? That is where laboratory outreach can make a difference. In outreach, a laboratory’s services become externally focused rather than only concentrating on the patients in hospital beds. It is the opposite of traditional lab medicine — it is entrepreneurial, intentional, and effective.

An emotional proposition for a pancreatic cancer survivor: Jim Smith
November 7, 2022

Since overcoming a life-threatening diagnosis five years ago, Jim Smith has embraced life. But each time he travels to Mayo Clinic for follow-up laboratory testing, a well of emotions rises up to remind him of life’s fragility. Thankfully, through streamlined, accurate testing and top-notch clinical care, those feelings are generally short-lived.

MayoComplete Next-Generation Sequencing: Oncology Subpanels
November 7, 2022

In this month's "Hot Topic," Kevin Halling, M.D., Ph.D., discusses new next generation sequencing testing for various tumor types and the rationale for the enhancements that were made; reviews gene additions that are now available in each of the panels; and briefly speaks about the work that was done to validate cytology specimens for use in the subpanels.

Week in Review: November 4
November 4, 2022

Topic highlights include: Mayo Clinic emergency medicine clinicians practice procedures with experts at "Skills Day," Flu season arrives early with highest severity in over a decade, FDA reports shortages of amoxicillin

The ABCs of CBD
November 4, 2022

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Paul Jannetto, Ph.D., associate professor of laboratory medicine and pathology at Mayo Clinic, and discusses how CBD can affect your health, what the medical benefits are, and its impact on urine drugs of abuse testing.

Thanksgiving specimen shipment alert
November 3, 2022

Due to the Thanksgiving holiday (recognized on Thursday, November 24th), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered. To ensure that your specimen vitality and turnaround times are not affected, plan ahead.

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