Genetics

Ann Moyer, M.D., Ph.D. gives an overview of this new test available through Mayo Clinic Laboratories. She discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be taken due to the results of this testing.

By Emily Linginfelter • August 1, 2019

PACE / State of CA / State of FL
This month’s “Virtual Lecture” discusses bleeding and clotting disorders with a focus on molecular testing.

By MCL Education • June 20, 2019

PACE
In this month’s “Virtual Lecture,” Kevin Halling, M.D., Ph.D., will review basic cancer genetics concepts and discuss examples of how RNA sequencing can be used to detect clinically relevant alterations in tumors such as gene fusions, point mutations, tumor mutation burden, and gene expression of individual genes or sets of genes.

By MCL Education • May 30, 2019

Dietrich Matern, M.D., Ph.D., Division Chair of Laboratory Genetics in the Department of Laboratory Medicine and Pathology in Rochester, Minnesota, has been appointed as a new director on the board of the American College of Medical Genetics and Genomics (ACMG).

By Molly Dee • April 12, 2019

Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a person’s genetic code.

By Barbara J. Toman • January 23, 2019

PACE / State of CA / State of FL
In this month’s “Virtual Lecture,” Katherine Geiersbach, M.D., and Ruifeng (Ray) Guo, M.D., Ph.D., will describe currently available testing offered in Mayo Clinic’s Genomics Laboratory and review the genetics of malignant progression in melanocytic lesions.

By MCL Education • January 22, 2019

This week’s Research Roundup highlights developmental delay and failure to thrive associated with a loss-of-function variant in WHSC1 (NSD2).

By Kelley Luedke • October 29, 2018

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is an autosomal dominant vascular dysplasia characterized by the presence of arteriovenous malformations of the skin, mucosa, and viscera. Linnea Baudhuin, Ph.D., FACMG, Co-Director of the Personalized Genomics Laboratory at Mayo Clinic, provides an overview of the new familial HHT gene panel available through Mayo Medical Laboratories. She discusses which types of patients should be tested, how this approach improves upon previous methods, and what clinical action can be taken from the results of this test.

By Alyssa Frank • September 19, 2018

Genetic testing is like security-camera video footage of a break-in, providing essential clues to identify a culprit. In certain cancers, the “culprit” might be a rearrangement in a person’s DNA, which genomic testing can capture. Mayo Clinic has developed a novel group of clinical tests that zoom in on a person’s genome to characterize chromosomal rearrangements.

By Barbara J. Toman • August 20, 2018

Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in Rochester, Minnesota, makes a case for pharmacogenomics.

By Kelley Luedke • July 2, 2018

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the North American Menopause Society found that genetic differences appear to play a role in the effectiveness of hormonal treatment for menopausal women.

By Mayo Clinic Center for Individualized Medicine • June 27, 2018

PACE / State of CA / State of FL
This month’s “Virtual Lecture” will discuss pharmacogenomics testing that is being performed at the Personalized Genomics Laboratory at Mayo Clinic.

By MCL Education • April 12, 2018

Mayo Medical Laboratories is the first clinical laboratory to offer postmortem genetic tests for inheritable cardiovascular disorders on formalin-fixed paraffin-embedded (FFPE) tissue as a preferred sample type.

By mayocliniclabs • April 10, 2018