Genetics

Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in Rochester, Minnesota, makes a case for pharmacogenomics.

By Kelley Luedke • July 2, 2018

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the North American Menopause Society found that genetic differences appear to play a role in the effectiveness of hormonal treatment for menopausal women.

By Mayo Clinic Center for Individualized Medicine • June 27, 2018

Mayo Medical Laboratories is the first clinical laboratory to offer postmortem genetic tests for inheritable cardiovascular disorders on formalin-fixed paraffin-embedded (FFPE) tissue as a preferred sample type.

By Mayo Clinic Laboratories • April 10, 2018

This week’s Research Roundup highlights patterns of homozygosity in patients with uniparental disomy with detection rate and suggested reporting thresholds for SNP microarrays.

By Kelley Luedke • April 2, 2018

Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month—a time to focus attention on the fight against multiple myeloma.

By Barbara J. Toman • March 6, 2018

Linnea Baudhuin, Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in Rochester, Minnesota, is featured in the American Association for Clinical Chemistry (AACC) Laborastories for genetic testing.

After being rushed to the ER on Valentine’s Day, a woman undergoes nine days of laboratory testing to find the [...]

By Kelley Luedke • January 23, 2018

This week’s Research Roundup highlights multifaceted Fanconi anemia signaling.

By Kelley Luedke • January 1, 2018

Researchers at Mayo Clinic have discovered a second-tier test for Pompe disease that has been shown to improve the specificity of newborn screening for the disorder, which would lower the rate of false-positive results.

By apriljosselyn • December 22, 2017

Hutton Kearney, Ph.D., Consultant of Hereditary Genomics Laboratory in the Division of Laboratory Genetics and Genomics at Mayo Clinic, participated in an interview with Frontline Genomics Magazine to discuss cytogenetics.

By Kelley Luedke • November 24, 2017

On the October 28 broadcast of Mayo Clinic Radio, Myra Wick, M.D., Ph.D., Consultant in the Division of Laboratory Genetics and Genomics at Mayo Clinic, explains the latest advances in prenatal screening.

By Kelley Luedke • November 10, 2017

The "Specialty Testing" webinar will briefly cover the current knowledge concerning the molecular genetic classification of adult gliomas.

By MCL Education • November 8, 2017

Ann Moyer, M.D., Ph.D., discusses an additional gene, NUDT15, which is important in the prediction of thiopurine-related toxicity This gene has been added to our TPMT genotyping assay available through Mayo Medical Laboratories.

By Mayo Clinic Laboratories • October 25, 2017

Ann Moyer, M.D., Ph.D., discusses the importance of pharmacogenomics testing to limit adverse drug reactions and the new focused pharmacogenomics panel available through Mayo Medical Laboratories.

By Mayo Clinic Laboratories • October 23, 2017