Hematology

This week’s Research Roundup highlights an assay to rapidly screen for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients and several other research articles by Mayo Clinic physicians and scientists.

By Alyssa Frank • March 11, 2019

Like a thief in the night, multiple myeloma sneaks up on people. The incurable blood cancer almost always starts as a relatively benign condition—monoclonal gammopathy of undetermined significance, or MGUS—that has no symptoms and often goes undiagnosed.

By Barbara J. Toman • January 11, 2019

Our Mayo Clinic colleagues are in San Diego for the 60th American Society of Hematology Annual Meeting and Exhibition. Follow this blog for live updates from #ASH18 as we attend the conference, mingle with colleagues at booth #2927, and have a little fun.

By Mayo Clinic Laboratories • December 3, 2018

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., describes how pseudohyperkalemia has many causes, from collection techniques, processing, and even transport. This presentation focuses on the various preanalytic and analytic causes of pseudohyperkalemia and what you as a phlebotomist can do to prevent it.

By Brad Karon, M.D., Ph.D. • September 10, 2018

Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month—a time to focus attention on the fight against multiple myeloma.

By Barbara J. Toman • March 6, 2018

This week’s Research Roundup highlights high grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology.

By Kelley Luedke • March 5, 2018

In this months "Hot Topic," Christopher Desens, MLS(ASCP) discusses the preparation of platelet-poor plasma for coagulation testing.

By MCL Education • September 17, 2017

This algorithm can be viewed here.

By Alyssa Frank • August 11, 2017

October 8, 2017 | Rochester, Minnesota
This symposium is designed for any provider who treats patients with hematologic malignancies (e.g., oncologists, hematologists, and physician assistants), pathologists, hematopathologists, cytogeneticists, laboratory directors, genetic counselors, and laboratory technologists and support staff.

By MCL Education • July 7, 2017

The algorithm can be viewed here.

By Alyssa Frank • July 1, 2017

In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.

By MCL Education • October 17, 2016

In this "Hot Topic," Dong Chen, M.D., Ph.D., describes how flow cytometry, electron micrographic study, and molecular testing are used to diagnose platelet function disorders.

By MCL Education • November 16, 2015

The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use of JAK2, CALR, and MPL mutational analysis in diagnosis and prognosis.

By MCL Education • July 15, 2015