Hematology

Utilizing testing capabilities of two separate laboratory facilities, Mayo Clinic Laboratories’ new serotonin release assay (SRA) is a gold-standard test supported by decades of clinical hematopathologic experience and advanced mass spectrometry testing.

By Robin Huiras-Carlson • November 9, 2022

Kenneth Hobby assumed his fever, fatigue, and aching pains in May 2018 were from another bout of malaria. He was on one of his frequent visits to Zambia in southern Africa, where the mosquito-borne parasite is common. But anti-malaria drugs didn't help, and soon Kenneth had such disabling pain that he could barely walk.

By Barbara J. Toman • September 5, 2022

Rong He, M.D., describes how Mayo Clinic Laboratories’ NPM1Q assay detects all known forms of a genetic mutation found in about 30% of people with acute myeloid leukemia, or AML. Identifying the NPM1 mutation is critical for clinical decision-making.

By Barbara J. Toman • August 9, 2022

Rajiv Pruthi, M.B.B.S., explains how Mayo Clinic Laboratories’ serotonin release assay achieves high sensitivity and specificity while avoiding the use of radioactive materials. Serotonin release testing is an important tool in the diagnosis of heparin induced thrombocytopenia, or HIT, which can have devastating consequences for patients.

By Barbara J. Toman • August 2, 2022

In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia (HIT), approach diagnosis, and the role of the functional serotonin release assay (SRA).

By MCL Education • August 1, 2022

In this month's "Hot Topic," Jess Peterson, M.D., discusses changes to Mayo Clinic Laboratories’ hematology FISH menu to increase awareness, provide reasoning, and highlight some of the great things that are coming.

By MCL Education • December 6, 2021

Michelle Kluge, M.S., CGC, explains how Mayo Clinic Laboratories’ CYPZ assay provides accurate testing for congenital adrenal hyperplasia. Using an in-depth methodology that incorporates Sanger sequencing, MCL can provide clear answers for carriers and individuals clinically affected by the most common form of CAH.

By Samantha Rossi • November 23, 2021

Andrew Feldman, M.D., discusses the different tools and techniques Mayo Clinic Laboratories uses to accurately diagnose and classify T-cell lymphomas to help provide clinicians with the diagnostic answers they need to treat their patients.

By Samantha Rossi • September 21, 2021

On Oct. 6‒8, 2021, Mayo Clinic Laboratories is hosting its 17th Bleeding and Thrombosing Diseases Conference and Workshop, and on Oct. 8-9, 2021, we’re also hosting a Non-Malignant Hematology Conference. Both conferences will be held in-person in Rochester, Minnesota, and also live-streamed online.

By Cory Pedersen • July 19, 2021

For patients with chronic lymphocytic leukemia (CLL) — the most common leukemia in adults — advanced testing can not only provide valuable information about their disease state, but peace of mind in the face of a progressive, incurable illness. Oftentimes, however, complex molecular and genetic tests to identify biomarker cues about disease trajectory and treatment intolerance are not performed, putting patients at risk for unmet expectations and unsatisfactory outcomes.

By Robin Huiras-Carlson • June 14, 2021

Meera Sridharan, M.D., Ph.D., explains Mayo Clinic Labs’ testing approach for atypical hemolytic uremic syndrome (aHUS). The serological complement panel examines nine analytes to gain a thorough understanding of the complement cascade to confirm diagnosis and direct care.

By Samantha Rossi • May 18, 2021

PACE/State of CA/State of FL - In this month’s “Virtual Lecture,” Justin Kreuter, M.D., goes over the importance of maintaining a healthy blood donor community by talking about the effects of blood donation on stored iron and describing which individuals are at a higher risk for iron deficiency anemia.

By MCL Education • April 22, 2021

The assay is now recommended for diagnosing and monitoring patients with monoclonal protein disorders and exclusively available through Mayo Clinic Laboratories– Rochester.

By Mayo Clinic Laboratories • March 16, 2021