Pathology

Explore why traditional microscopy is challenging, how AI-assisted review works, what workflow changes are required, and how validation data can support implementation decisions.

Mayo Clinic Laboratories is applying AI where it helps most today, strengthening daily workflows while keeping experts firmly in control. From faster specimen intake and triage to data‑informed scheduling, first‑pass support for complex analyses, draft interpretive reporting, and reliable digital pathology quantification, teams use AI to organize information, reduce repetitive steps, and improve consistency. Human‑in‑the‑loop oversight, fit‑for‑workflow design, and regulatory‑aware communication keep the focus on safe, practical gains that benefit patients, clinicians, and laboratorians.

PACE/FL - Explore how mass spectrometry serves as a powerful investigative tool

In a Fierce Healthcare article, Dr. William Morice highlights AI, digital pathology, and mass spectrometry as key advancements revolutionizing healthcare diagnostics and treatment.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Peter Lucas, M.D., Ph.D., vice chair of Research for the Department of Laboratory Medicine and Pathology (DLMP) at Mayo Clinic.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic.

Maryam Shahi, M.D., explains how Mayo Clinic Laboratories' unique biomarker test (TEST ID: AFOLR) determines which patients would likely benefit from a new treatment for recurrent epithelial ovarian cancer. Disease recurrence is common, and about one-third of patients respond to the new medication.

In a recent discovery by Mayo Clinic Laboratories, a novel hemoglobinopathy category was identified and termed epsilon gamma thalassemia. The first instance of the disorder was found in 2017 when an obstetric patient underwent a routine screening for blood-related illnesses such as sickle cell disease and thalassemia. Upon completion of additional tests, doctors found an abnormality they had never seen before.

Almost four years ago, Mayo Clinic launched the Digital Pathology Program, a major pathology initiative. Phase 2 of this multi-phase rollout has recently been completed, which involved the implementation of cutting-edge digital equipment and software, and converting glass slides of patient samples into digital images. The conversion enables pathologists and laboratory technologists to view, store, retrieve, and share medical images more universally, without waiting for glass slides to be retrieved and delivered. This has significantly improved patient care because pathologists can now discuss cases with clinicians and surgeons in real time.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss how representation and advocacy make a difference in regulatory outcomes.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, sits down with Joaquin Garcia, M.D., chair of Mayo Clinic’s Division of Anatomic Pathology and digital pathology program to discuss how the advent of digital pathology is changing patient care at Mayo Clinic.

Joseph Maleszewski, M.D., and Marie-Christine Aubry, M.D., explain how Mayo Clinic Laboratory can provide definitive diagnosis of primary ciliary dyskinesia (PCD). Mayo Clinic's expertise and technology have earned the laboratory's designation as the sole center of excellence for diagnosing this rare respiratory disorder.

Darci Block, Ph.D., of the Department of Laboratory Medicine and Pathology at Mayo Clinic, authored an article in the American Association for Clinical Chemistry’s (AACC) Clinical Laboratory News highlighting hurdles in body fluid testing.