Research Roundup

This week’s research roundup features a study on inherited pathogenic variants in PALB2 and the associated increased risk of breast and pancreatic cancer.

This week’s research roundup features a study on sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

This week’s research roundup features a phase two study of pembrolizumab combined with chemoradiotherapy as initial treatment for anaplastic thyroid cancer.

This week’s research roundup features a study on antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration.

This week’s research roundup features a study on glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to chemotherapy by abrogating the topBP1/ATR-mediated DNA damage response.

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews. This week's featured abstract is on discovery, validation, and application of novel methylated DNA markers for detection of esophageal cancer in plasma.

This week’s research roundup features a study on renal leiomyoma.

This week’s research roundup features a study on how mass cytometry dissects T cell heterogeneity in the immune tumor microenvironment of common dysproteinemias at diagnosis and after first line therapies.

This week's research roundup features mechanisms of lung disease development in patients with Rheumatoid Arthritis.

This week’s research roundup features a landmark study on optic neuritis.

This week’s research roundup features a clinical guide to hereditary cancer panel testing.

This week’s research roundup features research on the Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol.

This week's research roundup features research on the treatment of Membranous Nephropathy.