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Testing

Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer or HNPCC) is an autosomal dominant hereditary cancer syndrome associated with germline mutations in the mismatch repair genes, MLH1, MSH2, MSH6, and PMS2. Deletions within the 3' end of the EPCAM gene, which lead to inactivation of the MSH2 promotor, have also been associated with Lynch syndrome.

By Alyssa Frank • September 18, 2020

In August 2020, Mayo Clinic Laboratories announced five new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

By Alyssa Frank • September 14, 2020

The results are part of a comprehensive study of 16,175 cases performed at Mayo Clinic over an 11-year period.

By Suzanne Ferguson • September 10, 2020

Divyanshu (Div), Dubey, M.B.B.S, gives an overview of the new Autoimmune Gastrointestinal Dysmotility Evaluation available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action can be taken due to the results of this testing.

By Mayo Clinic Laboratories • September 3, 2020

The following list includes updates posted to mayocliniclabs.com during the month of August:

CPT Code and Test Classification Updates Test IDTest NameUpdatedZMMLS8073Antimicrobial Susceptibility, Aerobic Bacteria, VariesCPT Code Information8/14/2020 4:00pmCPDOE609632Convalescent Plasma Donor Evaluation, SerumCPT Code Information8/12/2020 12:07pmCVNFS609608Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody, Follow up, SerumCPT [...]
By Michael Hutchison • September 1, 2020

One of the biggest misunderstandings about genetic testing is a perception that once a variant is identified and analyzed thoroughly, using all the best tools available, it can be associated with a specific disease or condition. But many mutations are deemed “variants of unknown significance,” meaning there is no reported (or insufficient) evidence as to whether or not they cause disease.

By Christoph Bahn • August 27, 2020

Andrew McKeon, M.B., B.Ch., M.D, gives an overview of the new glycine receptor antibody test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to other testing approaches, and what clinical action can be taken due to the results of this testing.

By Alyssa Frank • August 19, 2020

In July 2020, Mayo Clinic Laboratories announced one new test along with numerous reference value changes, obsolete tests, and algorithm changes.

By Alyssa Frank • August 13, 2020

Horatiu Olteanu, M.D., Ph.D., gives an overview of the new T-cell receptor (TCR) β-chain constant region (TRBC1) flow cytometry marker, which is now included in Mayo Clinic Laboratories' routine diagnostic T-cell flow cytometry panel. He discusses when this testing should be ordered, how the addition of TCRBC1 compares to previous testing approaches, and how this marker can assist ordering physicians.

By Alyssa Frank • August 11, 2020

The following list includes updates posted to mayocliniclabs.com during the month of July:

CPT Code and Test Classification Updates Test IDTest NameUpdatedFFMDS75611FISH, MDS/Myeloid Panel, -5/5q-, -7/7q-, +8,20qCPT Code Information7/27/2020 12:05pmMITOT65212Combined Mitochondrial Analysis, Mitochondrial Full Genome and Nuclear Gene Panel, VariesTest Classification7/21/2020 4:03pmSYPHT603259Syphilis Total Antibody with Reflex, SerumCPT [...]
By Michael Hutchison • August 3, 2020

In the last decade or so, genetic testing has evolved from single-gene Sanger based assays to much more complex next-generation sequencing (NGS) based assays. This incredible technology has facilitated the rapid and high-throughput evaluation of many genes (hundreds of thousands of DNA strands) all at once.

By Christoph Bahn • July 29, 2020

Maria Willrich, Ph.D., gives an overview of the new Multiple Sclerosis Profile available through Mayo Clinic Laboratories. She discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action can be taken due to the results of this testing.

By Alyssa Frank • July 21, 2020

In June 2020, Mayo Clinic Laboratories announced three new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

By Alyssa Frank • July 16, 2020