Therapeutics

In a landmark discovery published in Clinical Chemistry, authenticated locks of hair from the composer Ludwig van Beethoven have revealed high lead concentrations after being analyzed at Mayo Clinic. Paul Jannetto, Ph.D., director of the Metals Laboratory at Mayo Clinic, along with his laboratory staff, completed testing on two independent and authenticated locks of Beethoven’s hair which confirmed the presence of high lead concentrations and could explain the cause for many of Beethoven’s ailments.

Paul Jannetto, Ph.D., explains the advantages that Mayo Clinic Laboratories' oral fluid drug screening offers over typical urine tests. Oral samples are easier to collect and harder to adulterate.

Tobacco use is the leading cause of preventable death in the United States. In this test-specific episode of the "Answers From the Lab" podcast, Paul Jannetto, Ph.D., explains how Mayo Clinic Laboratories' nicotine testing benefits patients in smoking cessation programs and other settings.

Recognizing the powerful role genes can play in diagnosing illness and guiding treatment, the Division of Laboratory Genetics and Genomics at Mayo Clinic spearheaded a testing expansion, implementing and upgrading more than 60 advanced sequencing and biochemical assays in 2023 and planning for even more this year.

Mark your calendar for Friday, April 12, and join Mayo Clinic Laboratories and Mayo Clinic's Department of Laboratory Medicine and Pathology for their 9th Annual Forensic Science Symposium in Rochester, Minnesota. This symposium will cover a wide range of topics, including water-related search and rescue, water-related deaths, firearms examination, deaths related to alcohol consumption, electrocution, huffing, and others.

Explore a diverse range of topics, from water-related search and rescue to firearms examination, at this exclusive symposium. Dive deep into real-world case studies covering deaths related to alcohol consumption, electrocution, huffing, and more. Participants will also have the opportunity to attend breakout sessions on search and rescue, firearms, and K9 units for hands-on learning.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Paul Jannetto, Ph.D., director of the Clinical and Forensic Toxicology Lab, Clinical Mass Spectrometry Lab, and Metals Lab at Mayo Clinic. Dr. Pritt and Dr. Jannetto discuss the current state of the opioid crisis in the United States, its impact on public health, and the important role of laboratory testing in addiction medicine and pain management patients.

In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine compliance to benzodiazepine therapy.

Visit Mayo Clinic Laboratories at booth #2047 to learn about our comprehensive therapeutics test offerings. Developed by board-certified experts in clinical chemistry, molecular, and toxicology testing, our testing is designed to detect and monitor therapeutic and illicit drugs across several relevant specimen types.

Join us for the APA Annual Meeting 2023, the premier event for psychiatrists and mental health professionals. This year's meeting will be held May 20–24 in San Francisco and will feature an exciting program of educational sessions, expert speakers, and networking opportunities.

Misdiagnosed with acromegaly, a disease marked by too much growth hormone, and plagued by a host of mysterious health problems from unnecessary medications, Kelly DuBois finally found answers after pharmacogenomic testing from Mayo Clinic Laboratories put her on a path toward healing.

Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories’ new marijuana monitoring evaluation, which identifies metabolites of both delta-9 tetrahydrocannabinol (THC) and delta-8 THC to accurately identify and characterize patients’ marijuana use.

For Billy Dowell Jr., a competitive golfer, focus, determination, and course correction are essential to excelling at the sport. These skills, along with routine follow-up care and testing, are also important to navigating a life impacted by multiple chronic autoimmune conditions.