As healthcare organizations continue to respond to COVID-19, Mayo Clinic Laboratories remains in full service for your reference laboratory needs. We offer a comprehensive menu of COVID-19 and related testing.

COVID-19 Test menu

Molecular (PCR) testing

Molecular testing is used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19. This real-time polymerase chain reaction (PCR) test can identify SARS-CoV-2 from a variety of clinical samples from patients with suspected COVID-19, including nasopharyngeal swabs and throat swabs.

Key testing


  • Distinguishes between persistent infection and re-infection in individuals with recurrent positive molecular test results for SARS-CoV-2.
  • Detects and identify vaccine-escape SARS-CoV-2 variants with spike (S) gene mutations of interest.
  • Detects and identify SARS-CoV-2 variants containing S gene mutations of interest that reduce the efficacy of vaccine-induced antibodies, convalescent plasma, or monoclonal antibody therapy for COVID-19.

Serology testing

Serologic, or antibody testing, is used to identify individuals who were previously infected with SARS-CoV-2. These individuals may have been symptomatic or asymptomatic. Serologic testing should not be used to diagnose active COVID-19 because the development of an immune or antibody response is delayed and can take 5 to 14 days after symptom onset to become detectable.  

Key testing

Related testing

Key testing


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