Autoimmune Pediatric Disorders

An evaluation designed specifically for children

This first-of-its-kind profile includes only the antibodies that are pertinent to pediatric CNS disorders—all in one evaluation. The antibodies included are supported by clinical research, and the results of this testing can help with diagnosis and long-term treatment planning.

11x

MOG antibody is 11 times more common
than AQP4 antibody in children.

When to consider testing

Consider testing for children under 18 with suspected autoimmune encephalitis, or other autoimmune presentation such as ataxia or autoimmune encephalomyelitis, with one or more of the following:

  • Rapid onset and progression of symptoms over weeks to months.
  • Behavioral changes such as unrelenting crying spells or tantrums—with or without clear cause—usually accompanied by one or more of the following: confusion, headaches, altered awareness, or movement disorder.

Which test should I order?

PCDEC | Pediatric Autoimmune CNS Evaluation, Spinal Fluid

PCDES | Pediatric Autoimmune CNS Evaluation, Serum

A Test in Focus

Autoimmune encephalitis and myelitis is increasingly recognized as a cause of CNS disease in children and teens. Andrew McKeon, M.B., B.Ch., M.D, gives an overview of this test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to other testing approaches, and what clinical action can be taken due to the results of this testing.

Learn More

Learn more about how to order this evaluation at your institution.

Antibodies included:

Plasma membrane specificities

Nuclear and cytoplasmic specificities

Additional Resources

Webinar - Pediatric CNS Disorders

This “Specialty Testing” webinar addresses the clinical presentations, evaluation (including diagnostic antibody testing), and treatment of autoimmune pediatric CNS disorders, including encephalitides and myelopathies.

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