Melanoma
Improve disease classification and guide therapy decisions
Melanoma accounts for just 1% of skin cancer diagnoses but causes the majority of skin cancer deaths.1 Because of the heterogeneity of melanoma and unique genetic features of the cancer, prognosis and treatment can vary greatly. Accurate classification of melanoma is vital to understanding both the illness’s implications on the patient and the best treatment plan.
Melanoma Test menu
Melanoma
Our MayoComplete melanoma panel uses next-generation sequencing to evaluate 17 melanoma-specific genes for variations related to diagnosis, prognosis, and tumor classification. Our team of board-certified geneticists and genetic counselors is available to assist with questions related to testing options and results interpretation.
Key testing
Advantages
- High accuracy and sensitivity.
- Helps distinguish between benign and malignant cases.
- Guides decisions on targeted treatment options.
- Developed, validated, analyzed, and interpreted by Mayo Clinic experts.
- Evaluates BAP1, BRAF, CDKN2A, CTNNB1, EIF1AX, GNA11, GNAQ, HRAS, KIT, KRAS, MAP2K1, MAP2K2, NF1, NRAS, SF3B1, TERT-promoter, and TP53 genes.
Highlights
Dr. Dong Chen and Dr. Sounak Gupta joined the “Becker’s Healthcare Podcast” to discuss the molecular testing space and its important role in personalized cancer treatment. Dr. Chen and Dr. Gupta highlighted the importance of selecting the right molecular tests for patients, the impact of genetic testing on cancer diagnosis and treatment, and how Mayo Clinic Laboratories is helping physicians make informed decisions for the best patient outcomes.
In this test specific episode of the "Answers From the Lab" podcast, Ruifeng (Ray) Guo, M.D., Ph.D., explains how Mayo Clinic Laboratories' comprehensive melanoma panel better informs prognosis and treatment.
References
- The American Cancer Society medical and editorial content team. Key Statistics for Melanoma Skin Cancer. American Cancer Society. Updated January 12, 2022. Accessed October 7, 2022. https://www.cancer.org/cancer/melanoma-skin-cancer/about/key-statistics.html
- New genetic regions linked to risk of melanoma. NIH Research Matters, National Institutes of Health. Published May 5, 2020. Accessed October 7, 2022. https://www.nih.gov/news-events/nih-research-matters/new-genetic-regions-linked-risk-melanoma