Guiding diagnosis, prognosis, and therapy options.
Our comprehensive test menu includes testing to aid in providing both diagnostic and prognostic information and in treatment selection across the full spectrum of malignancies. Each assay is developed and validated in collaboration with Mayo Clinic oncologists, pathologists, and laboratorians. Through our clinical experience and expertise, we strive to provide testing options that improve patient care, increase efficiency, and reduce costs.
Stay up-to-date on the latest discoveries and test launches. Sign up for our monthly oncology newsletter.
Additional Test Offerings
Results That Matter
We're dedicated to our patients' health and well-being,
and proud of the outstanding outcomes we achieve.
genetic tests developed for solid tumors
areas of specialized oncology testing
specializing in molecular and
cytogenetic diagnostic testing
support from Mayo Clinic physicians and scientists
Diagnostic, prognostic, and predictive testing
Our comprehensive menu offers testing to provide diagnostic and prognostic information and helps guide treatment selection across the full spectrum of malignancies. Our tumor-specific panels only include genes that are clinically proven to impact patient outcomes. This eliminates confusing results, decreases the cost of testing, and leads to better patient care.
Integration of clinical care, pathology, genetics, and bioinformatics
We take the lead in designing and optimizing testing to guide patient care based on specific tumors. Our experience with clinical care is integrated with our expertise in pathology, genetics, and bioinformatics to direct which genes are selected for each panel and how these panels are used in a clinical setting.
not just results
Genetic testing is about more than just determining whether a mutation is present or not. We take complex genetic results and turn them into clinically actionable answers. Our clinicians, laboratorians, and genetic counselors are available 24/7 to provide expertise and consultative support, eliminating the guesswork from results interpretation.
New Test Options for NTRK Gene Fusions
The presence of NTRK gene fusions is one of the eligibility requirements for the recently FDA-approved therapy Vitrakvi (larotrectinib), a therapy indicated in adult and pediatric patients with solid tumors regardless of the type of tumor. NTRK gene fusions have been described in many cancers at various frequencies, including common cancers such as lung, thyroid, and colorectal.
Lynch syndrome (also known as hereditary nonpolyposis colorectal cancer or HNPCC) is an autosomal dominant hereditary cancer syndrome associated with germline mutations in the mismatch repair genes, MLH1, MSH2, MSH6, and PMS2. Deletions within the 3' end of the EPCAM gene, which lead to inactivation of the MSH2 promotor, have also been associated with Lynch syndrome.
In the last decade or so, genetic testing has evolved from single-gene Sanger based assays to much more complex next-generation sequencing (NGS) based assays. This incredible technology has facilitated the rapid and high-throughput evaluation of many genes (hundreds of thousands of DNA strands) all at once.