Mayo Clinic Laboratories > Oncology > Melanoma

Melanoma

Improve disease classification and guide therapy decisions

Melanoma accounts for just 1% of skin cancer diagnoses but causes the majority of skin cancer deaths.1 Because of the heterogeneity of melanoma and unique genetic features of the cancer, prognosis and treatment can vary greatly. Accurate classification of melanoma is vital to understanding both the illness’s implications on the patient and the best treatment plan.

99K+

99K+ new melanomas diagnosed in 20221

~85

~85 genetic loci associated with melanoma2

17

17 genes associated with melanoma included on the MayoComplete melanoma panel

Melanoma Test menu

Melanoma Melanoma

Melanoma

Our MayoComplete melanoma panel uses next-generation sequencing to evaluate 17 melanoma-specific genes for variations related to diagnosis, prognosis, and tumor classification. Our team of board-certified geneticists and genetic counselors is available to assist with questions related to testing options and results interpretation.

Key testing

Advantages

  • High accuracy and sensitivity.
  • Helps distinguish between benign and malignant cases.
  • Guides decisions on targeted treatment options. 
  • Developed, validated, analyzed, and interpreted by Mayo Clinic experts.
  • Evaluates BAP1, BRAF, CDKN2A, CTNNB1, EIF1AX, GNA11, GNAQ, HRAS, KIT, KRAS, MAP2K1, MAP2K2, NF1, NRAS, SF3B1, TERT-promoter, and TP53 genes.
View now Hematology, oncology, and hereditary test selection guide

Highlights

Melanoma panel provides more tumor information

In this test specific episode of the "Answers From the Lab" podcast, Ruifeng (Ray) Guo, M.D., Ph.D., explains how Mayo Clinic Laboratories' comprehensive melanoma panel better informs prognosis and treatment.

Learn more
References
  1. The American Cancer Society medical and editorial content team. Key Statistics for Melanoma Skin Cancer. American Cancer Society. Updated January 12, 2022. Accessed October 7, 2022. https://www.cancer.org/cancer/melanoma-skin-cancer/about/key-statistics.html
  2. New genetic regions linked to risk of melanoma. NIH Research Matters, National Institutes of Health. Published May 5, 2020. Accessed October 7, 2022. https://www.nih.gov/news-events/nih-research-matters/new-genetic-regions-linked-risk-melanoma
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