Mayo Clinic Laboratories is integrated with Mayo Clinic’s anatomic pathology laboratories in the Department of Laboratory Medicine and Pathology. The fusion of our multispecialty pathology team with our comprehensive approach provides an ideal environment to diagnose rare and complex cases, while enabling the flexibility to keep care local.
6,500+ analyzed biopsies and delivered answers per year in our Renal Biopsy Laboratory
24/7 Mayo Clinic renal biopsy technicians and renal pathologists available for STAT diagnosis
280+ specialty stains and ancillary tests available
RENAL PATHOLOGY TEST MENU
All results include the following information-based standards for diagnostic evaluation and reporting of non-neoplastic renal disease:
The Mayo Clinic difference
Our highly trained laboratory techs have expertise in assessing and potentially reallocating LM and EM fixed tissues, which ensures adequacy of the material required for consultation. Additionally, when samples are submitted with limited or no tissue in the immunofluorescence preservative (Michel’s/Zeus), we can perform IF using a paraffin-based salvage technique. Combined, these techniques help facilitate diagnosis even in cases where a limited biopsy specimen is received.
We provide high-contrast images by using superior quality processing methods to generate samples for EM. This enables detection of abnormalities, such as amyloid fibrils, tubuloreticular inclusions, and subtle substructure in deposits that may not be visible in lower contrast images produced using rapid throughput methodologies.
Each member of our EM team completes a rigorous training process and recertification at specified intervals. This includes training to apply the same methodical approach for examining the four major tissue compartments — glomeruli, tubules, interstitium, and vessels — with increasing magnification. This provides clarity on the kidney structures and the location of abnormalities, such as deposits, providing pathologists a complete picture to secure the diagnosis.
Rapid turnaround times
Beyond the test result
The anatomic pathology laboratories’ eight-member team of renal pathologists collaborates with Mayo Clinic’s Division of Nephrology and Hypertension and holds special interests in non-neoplastic kidney disease. Our pathologists are available to offer support and strive for superior client communication.
To ensure accuracy and provide timely results, Mayo Clinic renal pathologists evaluate all specimens and report findings based on diagnostic standards of the Renal Pathology Society, Banff Conferences, and International Kidney and Monoclonal Gammopathy Research Group.
Standard pathology work-up receives the following testing:
In addition to pathology consultations, we offer a full menu of ancillary test options. Our tests include but are not limited to:
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