The Clinical and Forensic Toxicology Laboratory offers high-resolution, accurate mass spectrometry-based profiles to identify parent drugs and metabolites, including prescription drugs and illicit substances, to support patient rehabilitation and recovery. Utilization of emerging technologies in our assays enables increased specificity to detect the lowest levels of substances, which correlates to a reduction in false positives. This decreases the need for unnecessary confirmatory testing often required with traditional immunoassay screens.
Specimen validity testing
Effective monitoring of controlled substances and assessment for risk of misuse requires correct interpretation of test results. Because adulterated specimens can generate inaccurate results, having potentially damaging effects on treatment decisions, specimen validity testing is important to assess sample quality prior to testing and result interpretation.
Approximately eight percent of samples received at Mayo Clinic Laboratories for addiction rehabilitation monitoring were identified as adulterated.
Our controlled substance monitoring profiles begin with an adulterant survey to assess for common masking agents and ensure specimen quality. When adulterated specimens are identified, the test order is canceled and reported as invalid, free of charge to the client.
Interpretive reports
Laboratory-generated test results are accompanied by interpretive reports that clearly identify the presence of prescribed, nonprescription, and illicit drugs. By including testing limitations, details on the window of drug detection, and information on the presence of pharmaceutical impurities and metabolic breakdowns of parent drugs, these enhanced reports provide important insights to guide treatment decisions
Our industry-leading experts are available to discuss unexpected or unexplained results, provide ordering guidance, and offer testing education free of charge to our clients.
Comprehensive Urine Drug profiles test menu for ADDICTION rehabilitation monitoring
Our comprehensive addiction medicine profile can help identify polysubstance use disorder as well as assess and manage patients at risk for substance use disorder.
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Highlights
Bringing together advanced testing technology, unparalleled expertise, and a patient-focused approach, Mayo Clinic Laboratories’ new high-resolution urine drug testing profile, ADMPU, evaluates for 22 drug classes including alcohol, marijuana, and nicotine, enabling clarity on substance use and precision insights that propel treatment.
Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories' unique approach to urine drug testing for addiction rehabilitation. Designed to guide and monitor therapy, the comprehensive profile tests for the most commonly used substances, including alcohol and nicotine, for a complete picture of a patient’s substance use.
In instances where nicotine testing is not required, our enhanced controlled substance monitoring profile can provide accurate answers about other substance use.
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