Mayo Clinic Laboratories > Therapeutics > Controlled substance monitoring

Controlled substance monitoring

Mitigate risks for patients and physicians

Controlled substances are widely prescribed for a number of clinical indications; however, these substances have a high risk for misuse and diversion. To help clinicians manage the challenges of abuse presented by controlled substances, the American Association for Clinical Chemistry Academy developed Laboratory Medicine Practice Guidelines that recommend using clinical laboratory tests to monitor drug therapy in pain management patients.

The Clinical and Forensic Toxicology Laboratory at Mayo Clinic offers the industry’s most comprehensive evidence-based urine drug testing menu. Our profiles were developed with consistency to practice guidelines and help clinicians identify specific prescription drugs, adulterants, and illicit substances.

Testing services

News and updates

The latest

  1. Argoff CE, Kahan M, Sellers EM. Preventing and managing aberrant drug-related behavior in primary care: systematic review of outcomes evidence. J Opioid Manag. 2014;10(2):119–134.
  2. Key Substance Use and Mental Health Indicators in the United States: Results from the 2019 National Survey on Drug Use and Health
  3. U.S. Food & Drug Administration: Online Opioid Summits

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