Therapeutic drug monitoring

Personalizing medication selection

Therapeutic drug monitoring (TDM), or the quantification of drug concentrations in the blood over time, provides physicians and psychiatrists with a deeper understanding of a patient’s response to therapy.

In certain instances, such as for the management of major depressive disorder, TDM is vital for ensuring optimal treatment concentrations for patients. We offer a robust menu of assays to assist with monitoring antidepressants, mood stabilizers, and more.

Therapeutic drug monitoring test menu


Tricyclic antidepressants (TCAs)

Select serotonin reuptake inhibitors (SSRIs)

mood stabilizers

Key testing

  1. Undurraga J, Baldessarini RJ. Randomized, placebo-controlled trials of antidepressants for acute major depression: thirty-year meta-analytic review. Neuropsychopharmacology. 2012;37:851–64
  2. Tansey KE, Guipponi M, Hu X, et al. Contribution of common genetic variants to antidepressant response. Biol Psychiatry. 2013 Apr 1;73(7):679-82. doi:10.1016/j.biopsych.2012.10.030. Epub 2012 Dec 11. PMID: 23237317
  3. Hiemke C, Bergemann N, Clement HW, et al. Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology. Pharmacopsychiatry. 2018;51. 9-62.

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