Therapeutic drug monitoring

Personalizing medication selection

Therapeutic drug monitoring (TDM), or the quantification of drug concentrations in the blood over time, provides physicians and psychiatrists with a deeper understanding of a patient’s response to therapy.

In certain instances, such as for the management of major depressive disorder, TDM is vital for ensuring optimal treatment concentrations for patients. We offer a robust menu of assays to assist with monitoring antidepressants, mood stabilizers, and more.

Therapeutic drug monitoring test menu

Antidepressants

Tricyclic antidepressants (TCAs)

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Select serotonin reuptake inhibitors (SSRIs)


mood stabilizers

Key testing


References
  1. Undurraga J, Baldessarini RJ. Randomized, placebo-controlled trials of antidepressants for acute major depression: thirty-year meta-analytic review. Neuropsychopharmacology. 2012;37:851–64
  2. Tansey KE, Guipponi M, Hu X, et al. Contribution of common genetic variants to antidepressant response. Biol Psychiatry. 2013 Apr 1;73(7):679-82. doi:10.1016/j.biopsych.2012.10.030. Epub 2012 Dec 11. PMID: 23237317
  3. Hiemke C, Bergemann N, Clement HW, et al. Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology. Pharmacopsychiatry. 2018;51. 9-62. http://dx.doi.org/10.1055/s-0043-116492
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