PACE/State of FL - Register now – Sept. 10, 2025

Clinically relevant overview of key genetic factors, testing strategies, and post-result care.

Conflict is a natural part of human interaction, and the workplace is not immune from that experience.  Through this microlearning, we'll explore how proper conflict[...]

In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., along with the Lab Medicine Rounds podcast team share their experience on starting an educational podcast and reflecting on past episodes.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) recent approval of two gene therapies for sickle cell disease.

In this month's "Hot Topic," Nicole Boczek, Ph.D., assistant professor and laboratory director in the Department of Laboratory Medicine and Pathology, and Sarah Barnett, M.S., CGC, discuss diagnostic exploratory testing, explain why it’s important to the field of many specialty practice areas, and help determine which testing may be the most valuable for a given patient.

In her current role as senior manager for global logistics at Mayo Clinic Laboratories, Sarah Mason oversees the coordination of patient sample shipments by working with a network of stakeholders, couriers, carriers, and vendors. Sarah emphasizes the critical nature of safe and timely delivery of more than 38,000 samples each day, highlighting the dynamic challenges in healthcare logistics. Through her work, she finds meaning and purpose in collaborating with diverse teams to bring impactful change to Mayo Clinic operations and its patients.

Maria Willrich, Ph.D., and Melissa Snyder, Ph.D., describe Mayo Clinic Laboratories' panel for proactive therapeutic drug monitoring of patients with inflammatory bowel disease. The panel expands options for clinicians assessing patients' response to infliximab and adalimumab.

This week's research roundup feature: Most patients with solitary bone plasmacytomas (SBP) progress to multiple myeloma (MM) after definitive radiation therapy as their primary treatment. Whether the presence of high-risk (HR) cytogenetic abnormalities by fluorescence in situ hybridization (FISH) in the clonal plasma cells, obtained either directly from the diagnostic SBP tissue or the corresponding bone marrow examination at the time of diagnosis, is associated with a shorter time to progression (TTP) to MM is unknown. This study evaluated all patients diagnosed with SBP at the Mayo Clinic from January 2012 to July 2022.

With all the preparations required to ready a clinical laboratory for regulatory inspection, it can be easy to overlook offsite testing locations, especially those performing CLIA-waived tests. Hospital laboratories with a CLIA Certificate of Compliance or Certificate of Accreditation may also oversee waived testing sites, and it is important to remember that those locations have as much potential for citations as the larger testing departments. Remember to give these five key areas special attention during inspection preparation.

One summer morning, James Kypuros awoke to find his toes stiffened like claws. Then he started having falls, which culminated in losing his ability to walk or even sit up without help. Diagnosed with stiff-person syndrome, James wouldn’t find hope or relief until he was treated for glycine receptor antibody syndrome following specialized testing by Mayo Clinic.

The United States will observe the New Year holiday on Monday, Jan. 1. On this day, Mayo Clinic Laboratories will be open; however, specimen shipments and deliveries to our laboratories will not be made by the carriers. To safeguard specimens, please follow these shipping recommendations.

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) proposed rule on laboratory-developed tests (LDTs) and the comments Mayo Clinic submitted to the FDA.

This week's research roundup feature: No human rabies post-exposure prophylaxis (PEP) failure has been documented in the United States using modern cell culture-based vaccines. In January 2021, an 84-year-old male died from rabies 6 months after being bitten by a rabid bat despite receiving timely rabies PEP. We investigated the cause of breakthrough infection.

The United States will observe the Christmas holiday on Monday, Dec. 25. On this day, Mayo Clinic Laboratories will be open; however, specimen shipments and deliveries to our laboratories will not be made by the carriers. To safeguard specimens, please follow these shipping recommendations.