MCL

Due to the Labor Day holiday (recognized on Monday, September 6), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered.

In 1971, the Regional Laboratory, later to become Mayo Clinic Laboratories, was founded. For the first time in Mayo Clinic’s history, the institution would support the community practice of pathology for outside patients in the region and beyond.

It’s been understood for some time that an infection of B. mayonii, a rare species of bacterium, results in high levels of spirochetes in the peripheral blood. But actually being able to visualize them on a routine peripheral blood smear may allow for improved recognition of this uncommon cause of Lyme disease.

The following list includes updates posted to mayocliniclabs.com during the month of July.

In this month’s “Hot Topic,” Julia Lehman, M.D., discusses a recent change to the direct immunofluorescence assay, specifically the addition of the IgG4 conjugate.

Mayo Clinic is harnessing the extraordinary potential of digital pathology through a robust initiative that’s using the technology to enhance patient care. Mayo’s Dermatology Department is an early adopter, and clinicians, students, and patients are all reaping the benefits.

Mayo Clinic Laboratories reaches patients around the globe. Alumni magazine highlights this work as it details the labs' international strategy.

Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory in Mayo Clinic’s Division of Clinical Microbiology, considers the prospects for COVID-19 this fall as the traditional influenza season ramps up.

In this episode of Lab Medicine Rounds, Dr. Daniela Hermelin, an Assistant Professor of Pathology at Saint Louis University School of Medicine and Medical Director of Transfusion Medicine Services at SSM Health St. Louis University Hospital and Cardinal Glennon Children's Hospital, discusses what learners should pay attention to during training to be successful in real life.

The discovery of Kelch like protein 11 (KLHL11) IgG as a specific biomarker of neurological autoimmunity associated testicular germ cell tumor.

Mayo Clinic renal pathologist Dr. Sanjeev Sethi identified NELL-1 as a biomarker for membranous nephropathy (MN) in 2019. Two years later, Dr. Sethi helped implement the first ever IHC test to detect NELL-1 antigen, which appears in about 10% of MN patients and is linked to underlying malignancy.

Mayo Clinic’s Advanced Diagnostics Laboratory (ADL) is a visionary space designed to foster innovation. The ADL has a direct impact on patient lives, bringing promising tests and services to patients at Mayo and around the world.

Pua Hopson, D.O., discusses Mayo Clinic Labs’ new disaccharidase activity panel, which measures levels of five digestive enzymes to identify deficiencies that cause carbohydrate maldigestion and can lead to chronic conditions like celiac disease or inflammatory bowel disease. Performed on tissue sample biopsies during upper endoscopy, the activity panel is the gold standard test for detecting disaccharidase deficiencies.