Research

This week’s research roundup features a study on amyloidosis in surgically resected atrial appendages and the clinical impact on 345 consecutive cases.

By Samantha Rossi • November 25, 2019

This week’s research roundup features a study on how integration of comprehensive genomic analysis and functional screening of affected molecular pathways inform cancer therapy.

By Samantha Rossi • November 18, 2019

This week’s research roundup features a study on how selective YAP/TAZ inhibition in fibroblasts via dopamine receptor DI agonism reverses fibrosis.

By Samantha Rossi • November 11, 2019

This week’s research roundup features coexistence of myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies in adult and pediatric patients.

By Samantha Rossi • November 4, 2019

This week’s research roundup features a study on inherited pathogenic variants in PALB2 and the associated increased risk of breast and pancreatic cancer.

By Samantha Rossi • October 28, 2019

This week’s research roundup features a study on sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

By Samantha Rossi • October 21, 2019

This week’s research roundup features a phase two study of pembrolizumab combined with chemoradiotherapy as initial treatment for anaplastic thyroid cancer.

By Samantha Rossi • October 14, 2019

This week’s research roundup features a study on antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration.

By Samantha Rossi • October 7, 2019

A Mayo Clinic study published in The New England Journal of Medicine finds that lung injuries from vaping most likely are caused by direct toxicity or tissue damage from noxious chemical fumes.

By Mayo Clinic News Network • October 3, 2019

This week’s research roundup features a study on glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to chemotherapy by abrogating the topBP1/ATR-mediated DNA damage response.

By Samantha Rossi • September 30, 2019

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews. This week’s featured abstract is on discovery, validation, and application of novel methylated DNA markers for detection of esophageal cancer in plasma.

By Samantha Rossi • September 23, 2019

This week’s research roundup features a study on renal leiomyoma.

By Samantha Rossi • September 16, 2019

This week’s research roundup features a study on how mass cytometry dissects T cell heterogeneity in the immune tumor microenvironment of common dysproteinemias at diagnosis and after first line therapies.

By Samantha Rossi • September 9, 2019