This week’s Research Roundup highlights biphenotypic acute leukemia versus myeloid antigen-positive ALL: Clinical relevance of WHO criteria for mixed phenotype acute leukemia.

This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.

The use of mud or wet clay as a topical skin treatment or a poultice is a common practice in some cultures and the concept of using mud as medicine goes back to earliest times. Now Mayo Clinic researchers and their collaborators at Arizona State University have found that at least one type of clay may help fight disease-causing bacteria in wounds, including some treatment-resistant bacteria.

This week’s Research Roundup highlights how fasting blood glucose levels provide an estimate of duration and progression of pancreatic cancer before diagnosis.

This week’s Research Roundup highlights diagnostic thresholds for androgen-producing tumors or pathologic hyperandrogenism in women by use of total testosterone concentrations measured by liquid chromatography-mass spectrometry.

A research team led by Fergus Couch, Ph.D., a geneticist at Mayo Clinic, has identified specific genes associated with an increased risk for developing triple-negative breast cancer. The team’s research was published in the Journal of the National Cancer Institute.

This week’s Research Roundup highlights how a novel enhancer regulates MGMT expression and promotes temozolomide-resistance in glioblastomas.

This week’s Research Roundup highlights a randomized trial of spheroid reservoir bioartificial liver in Porcine model of post-hepatectomy liver failure.

This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of immunoglobulin G4-related disease.

This week’s Research Roundup highlights how senolytics improve physical function and increase lifespan in old age.

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

This week’s Research Roundup highlights the comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor.

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the North American Menopause Society found that genetic differences appear to play a role in the effectiveness of hormonal treatment for menopausal women.