Research

This week’s research roundup features a study on glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to chemotherapy by abrogating the topBP1/ATR-mediated DNA damage response.

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews. This week's featured abstract is on discovery, validation, and application of novel methylated DNA markers for detection of esophageal cancer in plasma.

This week’s research roundup features a study on renal leiomyoma.

This week’s research roundup features a study on how mass cytometry dissects T cell heterogeneity in the immune tumor microenvironment of common dysproteinemias at diagnosis and after first line therapies.

This week's research roundup features mechanisms of lung disease development in patients with Rheumatoid Arthritis.

This week’s research roundup features a landmark study on optic neuritis.

This week’s research roundup features a clinical guide to hereditary cancer panel testing.

Traditionally, Mayo Clinic's Simulation Center is used for surgical procedures and teaching students how to run a code. Mayo Clinic pathology consultant Karen Fritchie, M.D., recently developed a new and innovative way to use the center.

This week’s research roundup features research on the Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol.

This week's research roundup features research on the treatment of Membranous Nephropathy.

This week's research roundup features a study on methylated DNA in pancreatic juice distinguishes patients with pancreatic cancer from controls.

This week's research roundup features research on novel methylated DNA markers discriminate advanced neoplasia in Pancreatic Cysts, what we are really looking for in a letter of recommendation, and more.

This week's research roundup features research on the characterization of the obese phenotype of heart failure with preserved ejection fraction: A RELAX Trial Ancillary Study.