This week’s Research Roundup highlights how the genome-wide analyses as part of the International FTLD-TDP Whole-Genome Sequencing Consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

This week’s Research Roundup highlights how the EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis.

Mayo Clinic researchers are tracking the familiar characteristics of kidney stone formers in an online prediction tool that could help sufferers anticipate if they’ll experience future episodes.

This week’s Research Roundup highlights the diagnostic accuracy of echocardiography and intraoperative surgical inspection of the unicuspid aortic valve.

This week’s Research Roundup highlights the diagnostic accuracy of echocardiography and intraoperative surgical inspection of the unicuspid aortic valve.

Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a person’s genetic code.

This week’s Research Roundup highlights the implementation of a reformulated Roche® Bilirubin Gen.3 reagent did not affect the relationship between BiliChek transcutaneous and Roche total serum bilirubin.

Mayo Clinic researchers report that spinal cord inflammation associated with an antibody to myelin oligodendrocyte glycoprotein can mimic acute flaccid myelitis, a rare but serious disease linked to certain viruses that particularly affects children and can result in paralysis.

Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, Mayo Clinic has discovered.

This week’s Research Roundup highlights the identification of prognostic phenotypes of esophageal adenocarcinoma in two independent cohorts.

This week’s Research Roundup highlights the role of 3D-MRE in the diagnosis of NASH in obese patients undergoing bariatric surgery.

This week’s Research Roundup determines the clinical validity of hereditary colorectal cancer and polyposis susceptibility genes using the clinical genome resource clinical validity framework.

This week’s Research Roundup highlights phosphorylated RB promotes cancer immunity by inhibiting NF-κB activation and PD-L1 expression.