Research

A research team led by Fergus Couch, Ph.D., a geneticist at Mayo Clinic, has identified specific genes associated with an increased risk for developing triple-negative breast cancer. The team’s research was published in the Journal of the National Cancer Institute.

By Mayo Clinic News Network • August 13, 2018

This week’s Research Roundup highlights how a novel enhancer regulates MGMT expression and promotes temozolomide-resistance in glioblastomas.

By Kelley Luedke • August 6, 2018

This week’s Research Roundup highlights a randomized trial of spheroid reservoir bioartificial liver in Porcine model of post-hepatectomy liver failure.

By Kelley Luedke • July 30, 2018

This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of immunoglobulin G4-related disease.

By Kelley Luedke • July 23, 2018

This week’s Research Roundup highlights how senolytics improve physical function and increase lifespan in old age.

By Kelley Luedke • July 16, 2018

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

By Kelley Luedke • July 9, 2018

This week’s Research Roundup highlights the comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor.

By Kelley Luedke • July 2, 2018

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the North American Menopause Society found that genetic differences appear to play a role in the effectiveness of hormonal treatment for menopausal women.

By Mayo Clinic Center for Individualized Medicine • June 27, 2018

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

By Kelley Luedke • June 25, 2018

According to Mayo Clinic research published in JAMA, six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer.

By Mayo Clinic News Network • June 21, 2018

Just as money in the bank boosts your financial well-being, biobanks have the power to impact your health. Think of biobank samples as assets that researchers can draw upon to improve disease treatments.

By Barbara J. Toman • June 19, 2018

This week’s Research Roundup features highly discriminant methylated DNA markers for the non-endoscopic detection of Barrett’s esophagus.

By Kelley Luedke • June 18, 2018

Mayo Clinic laboratory workers have a new tool to perform high tech genetic sleuthing for the source of stubborn, sometimes life-threatening bacteria.

By Mayo Clinic Center for Individualized Medicine • June 12, 2018