Research

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the North American Menopause Society found that genetic differences appear to play a role in the effectiveness of hormonal treatment for menopausal women.

By Mayo Clinic Center for Individualized Medicine • June 27, 2018

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

By Kelley Luedke • June 25, 2018

According to Mayo Clinic research published in JAMA, six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer.

By Mayo Clinic News Network • June 21, 2018

Just as money in the bank boosts your financial well-being, biobanks have the power to impact your health. Think of biobank samples as assets that researchers can draw upon to improve disease treatments.

By Barbara J. Toman • June 19, 2018

This week’s Research Roundup features highly discriminant methylated DNA markers for the non-endoscopic detection of Barrett’s esophagus.

By Kelley Luedke • June 18, 2018

Mayo Clinic laboratory workers have a new tool to perform high tech genetic sleuthing for the source of stubborn, sometimes life-threatening bacteria.

By Mayo Clinic Center for Individualized Medicine • June 12, 2018

This week’s Research Roundup highlights the detection of gastric cancer with novel methylated DNA markers: discovery, tissue validation, and pilot testing in plasma.

By Kelley Luedke • June 11, 2018

Since ancient times, physicians have analyzed patient specimens to diagnose illness. Now, our samples can do far more than diagnose. They can help researchers find treatments for the unmet needs of patients.

By Mayo Clinic Discovery's Edge • June 5, 2018

This week’s Research Roundup highlights isolated hepatic non-obstructive sinusoidal dilatation, a 20-year single center experience.

By Kelley Luedke • June 4, 2018

This week’s Research Roundup highlights the clinical and pathology findings associated consistently with larger glomerular volume.

By Kelley Luedke • May 28, 2018

This week’s Research Roundup highlights the development and validation of a prostate cancer genomic signature that predicts early androgen deprivation therapy (ADT) treatment response following radical prostatectomy.

By Kelley Luedke • May 21, 2018

Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of these efforts. The Center for Individualized Medicine is unraveling the complex behavior of melanoma at the molecular level—to allow for treatment that better targets an individual’s disease.

By Barbara J. Toman • May 15, 2018

This week’s Research Roundup highlights potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations.

By Kelley Luedke • May 14, 2018