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Chromosomal microarray testing

Subtext here to give overview of testing.

Superior analysis of copy number deletions and duplications

Chromosomal microarray provides high-resolution assessment of copy number variations across the genome. This includes superior analysis of the 1p/19q deletion in gliomas. Additionally, microarray detects abnormalities such as the gain of chromosome 7, loss of chromosome 10, and EGFR amplification. According to recently published guidelines, when these abnormalities are found in diffuse astrocytic gliomas, IDH-wildtype, the tumor should be considered as having molecular features of glioblastoma. Copy number variations can also further clarify or support diagnosis and provide information useful for prognosis.

Which test should I order?


A Test in Focus

Robert Jenkins, M.D., gives an overview of CMA testing for gliomas. He discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action can be taken due to the results of this testing.