Mayo Clinic Laboratories > Hematology > Coagulation disorders

Coagulation disorders

A patient-centered, value-based approach to testing

Our Special Coagulation Laboratory has been at the forefront of patient-centered and value-based diagnostic laboratory testing, research, and patient management for nearly 90 years. Led by a multidisciplinary team of physicians, the laboratory offers a broad repertoire of coagulation tests covering a wide spectrum of bleeding, thrombosing, and platelet disorders.

32

32 profiles focusing on bleeding, thrombosing, and platelet disorders

60+

60+ esoteric coagulation test offerings available outside of the profile testing menu

350,000

350,000 special coagulation tests performed annually

Anticoagulant drug monitoring Anticoagulant drug monitoring
Anticoagulant drug monitoring

Our Special Coagulation Laboratory offers clients access to a growing menu of special coagulation drug assays.

Bleeding disorders testing Bleeding disorders testing
Bleeding disorders testing

Our Special Coagulation Laboratory offers algorithmic approaches to meet your bleeding disorder testing needs.

Next-generation sequencing Next-generation sequencing
Next-generation sequencing

Created to meet the growing needs of our own clinical practice, we offer a comprehensive next-generation sequencing menu for patients who have bleeding and thrombosis disorders.

Platelet testing Platelet testing
Platelet testing

Genotype assays for bleeding, thrombosis, and platelet disorders are increasing in utility and availability. We offer a comprehensive next-generation sequencing menu for patients with these disorders.

Serotonin release assay Serotonin release assay
Serotonin release assay

Our serotonin release assay is the gold standard diagnostic test for detecting clinically relevant (platelet-activating) heparin-induced thrombocytopenia (HIT) antibodies.

Thrombophilia testing Thrombophilia testing
Thrombophilia testing

Whether acquired or inherited, the underlying causes of thrombophilia can be very diverse. Our Special Coagulation Laboratory offers a number of algorithmic approaches to thrombophilia testing.

Thrombotic microangiopathy (TMA) Thrombotic microangiopathy (TMA)
Thrombotic microangiopathy (TMA)

Because of the variety of TMA disorders and different treatment options for each, prompt and accurate diagnosis can significantly impact a patient’s outcome.

An algorithmic and cost-effective testing method

Our coagulation-focused algorithms were developed collaboratively among physicians, pathologists, laboratorians, and genetic counselors. These algorithms recommend approaches for diagnosis of specific diseases and assist in treatment and monitoring of patient care. In addition, they guide proper and cost-effective test utilization (e.g., activated protein C resistance testing with reflex to factor V Leiden analysis).

News and updates

The latest

Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes

PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and monoclonal gammopathy of thrombotic significance (MGTS), and focuses on impacts related to diagnosis for anti-platelet factor 4-mediated thrombotic syndromes.

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