An expanding geographic threat    

A full testing menu supported by an algorithmic approach to optimize diagnosis

Tick-borne diseases (TBDs) occur worldwide, but historically, only certain pockets of the United States posed a risk for infection. However, the geographic range of ticks continues to expand in North America, leading to higher risks of TBD exposure for the public. As a result of increasing exposure and the rising number of potential tick-borne pathogens, it is increasingly important to recognize who to test, when to test, and what test to use for patients who present with TBD symptoms.

We offer a full menu of individual tests and panels that aid in the diagnosis of TBDs. In addition to our comprehensive testing menu, we have developed multiple TBD testing algorithms, including modified two-tiered assays, to help guide and optimize diagnostic testing.

Tick-borne testing algorithms and interpretations

Testing algorithm

Key Serological Panels

STICK  | Tick-Borne Antibodies with 2-Tier Enzyme-Linked Immunosorbent Assay Lyme, Serum

Includes

TICKS  | Tick-Borne Disease Antibodies Panel, Serum

Includes

EHBAP  | Ehrlichia/Babesia Antibody Panel, Immunofluorescence, Serum

Includes

Key Molecular Panels

TIKLB   | Tick-Borne Panel, Molecular Detection, PCR, Blood

Includes

Lyme disease

SLYME  | Lyme Antibody Modified 2-Tier with Reflex, Serum

TLYME  | Lyme Antibody IgM and IgG by Whole Cell Sonicate, Enzyme-Linked Immunosorbent Assay, Serum

LNBAB   | Lyme Central Nervous System Infection IgG with Antibody Index Reflex, Serum and Spinal Fluid

LYME  | Lyme Disease Serology, Serum

LYWB   | Lyme Disease Antibody, Immunoblot, Serum

  • NOTE: Not recommended to perform without initial positive first-tiered equivocal Lyme enzyme immunoassay

ELYME   | Lyme Disease European Antibody Screen, Serum

ELYMI | Lyme Disease European Immunoblot, Serum

LYMPV   | Lyme Disease, Molecular Detection, PCR, Varies

PBORB  | Lyme Disease, Molecular Detection, PCR, Blood

  • NOTE: Not recommended to perform with concurrent Lyme disease serology testing (Mayo ID: LYME)

Babesiosis

BABG  | Babesia microti IgG Antibodies, Serum

BABPB  | Babesia species, Molecular Detection, PCR, Blood

Anaplasmosis

ANAP    | Anaplasma phagocytophilum (Human Granulocytic Ehrlichiosis) Antibody, Serum

EPCRB   | Ehrlichia/Anaplasma, Molecular Detection, PCR, Blood

Ehrlichiosis

EHRCP | Ehrlichia Antibody Panel, Serum

EHRC | Ehrlichia chaffeensis (HME) Antibody, IgG, Serum

Powassan virus

POWV   | Powassan Virus, IgM, Enzyme-Linked Immunosorbent Assay, Serum

POWVB   | Powassan Virus, RNA, Molecular Detection, PCR, Blood

POWVC   | Powassan Virus, RNA, Molecular Detection, PCR, Spinal Fluid

POWVS   | Powassan Virus, RNA, Molecular Detection, PCR, Serum

POWVU   | Powassan Virus, RNA, Molecular Detection, PCR, Random, Urine

Rocky Mountain spotted fever

SFGP   | Spotted Fever Group Antibody, IgG and IgM, Serum

Borrelia miyamotoi disease

BMIYB   | Borrelia miyamotoi Detection PCR, Blood

BMIYC  | Borrelia miyamotoi Detection PCR, Spinal Fluid

Alpha-gal Syndrome

ALGAL | Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum

APGAL  | Galactose-Alpha-1,3-Galactose (Alpha-Gal) Mammalian Meat Allergy Profile, Serum

Learn the ABCs of ticks

During the summer months, the great outdoors can be a wonderland for exploration. But some of nature’s inhabitants can be dangerous and even life-threatening. Though small, ticks are among nature’s most successful predators, with the capability to pass along numerous infectious illnesses to unsuspecting hosts. Knowing how to avoid ticks and their disease-spreading bites is as simple as learning the ABCs.

Learn more

Learn more about how to order these tests at your institution.