An expanding geographic threat    

A full testing menu supported by an algorithmic approach to optimize diagnosis

Tick-borne diseases (TBDs) occur worldwide, but historically, only certain pockets of the United States posed a risk for infection. However, the geographic range of ticks continues to expand in North America, leading to higher risks of TBD exposure for the public. As a result of increasing exposure and the rising number of potential tick-borne pathogens, it is increasingly important to recognize who to test, when to test, and what test to use for patients who present with TBD symptoms.

We offer a full menu of individual tests and panels that aid in the diagnosis of TBDs. In addition to our comprehensive testing menu, we have developed multiple TBD testing algorithms, including modified two-tiered assays, to help guide and optimize diagnostic testing.

Tick-borne testing algorithms and interpretations

Key Serological Panels

Key Molecular Panels

Lyme disease

LYWB   | Lyme Disease Antibody, Immunoblot, Serum

  • NOTE: Not recommended to perform without initial positive first-tiered equivocal Lyme enzyme immunoassay

PBORB  | Lyme Disease, Molecular Detection, PCR, Blood

  • NOTE: Not recommended to perform with concurrent Lyme disease serology testing (Mayo ID: LYME)




Powassan virus

Rocky Mountain spotted fever

Borrelia miyamotoi disease

Alpha-gal Syndrome

Learn the ABCs of ticks

During the summer months, the great outdoors can be a wonderland for exploration. But some of nature’s inhabitants can be dangerous and even life-threatening. Though small, ticks are among nature’s most successful predators, with the capability to pass along numerous infectious illnesses to unsuspecting hosts. Knowing how to avoid ticks and their disease-spreading bites is as simple as learning the ABCs.

Learn more about how to order these tests at your institution.