Ending diagnostic odysseys and inspiring hope
For patients with rare and complex conditions, physicians and other healthcare professionals need trusted answers. Our tests are developed through leading-edge research and unmatched clinical expertise, creating a diagnostics ecosystem that delivers insights that set a new standard in diagnostic care.
Successful patient outcomes are our priority, and we work with hospitals and physicians around the world to elevate diagnostic excellence everywhere. As part of Mayo Clinic’s healthcare system, we understand the best care is provided locally. We complement local expertise by working with clients and logistics organizations to optimize the specimen journey to our laboratories, enabling physicians to get the results they need and patients to remain at home, focused on healing.
Relentless pursuit of answers
Ongoing research propels test development at Mayo Clinic Laboratories, enabling innovative testing that delivers faster, reliable answers to confidently diagnose patients. Our test results not only equip physicians and patients with meaningful diagnostic, prognostic, and therapeutic insights, they also provide hope for a healthier future.
Experience and expertise you can trust
Mayo Clinic Laboratories’ scientists and physicians are leaders in their fields and able to consult on test selection, utilization, and results interpretation. The exchange of knowledge is a founding principle of Mayo Clinic, and we are committed to sharing lessons we’ve learned with our global collaborators through educational opportunities to help improve care delivery in local practices. This is supported through an expansive library of educational content, podcasts, and stories that showcase breakthroughs in test development and perspectives from Mayo Clinic experts.
Access to groundbreaking diagnostics
Driven by an instinct to innovate, we transform scientific discoveries into meaningful advancements in diagnostic testing. Supported by a robust network of Mayo Clinic physicians and scientists and forward-thinking laboratory partners, we foster access to new and advanced testing, much of which is unavailable elsewhere. This integration connects physicians and hospitals around the world with multiple innovative solutions all in one place to support better patient outcomes.
“We treat all of the specimens we receive with the same high degree of care and quality, regardless of where the sample is coming from. We could be testing a sample from a patient that lives in Rochester, Minnesota, or from someone that lives halfway across the world.”
Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory
OUR DIFFERENCE
News and updates
The latest
We are excited to announce that registration is now open for the 2026 Mayo Clinic Classical Hematology Conference: Nonmalignant Hematology and Bleeding and Thrombotic Disorders.
Register now – Aug. 11, 2026 Four case studies to explore key diagnostic considerations when Lyme testing is negative, highlight the role of geographic exposure history, and demonstrate the utility of multiplex testing panels
Due to the Memorial Day holiday (recognized on Monday, May 25), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered. To ensure that your specimen vitality and turnaround times are not affected, please note the following plans for Domestic and International shipping.
Discover how efficient, evidence-based serologic testing algorithms can accelerate Coccidioides infection diagnosis, simplify laboratory workflow, and provide practical benefits for laboratorians and healthcare professionals.
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to reflect on the essential role of laboratory medicine during National Medical Laboratory Professionals Week. Dr. Pritt also welcomes Julia Lehman, M.D., a dermatologist and dermatopathologist at Mayo Clinic, to discuss innovative diagnostic tests for autoimmune diseases affecting the skin.
New wtRNA-seq test detects fusions in 1,445 genes with high accuracy, improving cancer diagnosis, treatment decisions, and clinical trial eligibility.
This webinar will discuss how autoimmune neurology testing has changed with expanding antibody discovery and why a patient-first, phenotype-specific approach improves test selection and interpretation.
Mayo Clinic Laboratories’ MS testing cascade, which starts with kappa free light chain (KFLC) testing and reflexes to oligoclonal banding when indicated, is supported by the revised 2024 McDonald Criteria. This approach delivers faster, more definitive results, enabling earlier treatment decisions and improved patient outcomes.
A young dancer from Minnesota thrives with a rare blood disorder, thanks to resilience, family advocacy, and lifesaving lab medicine.
PACE / State of FL - Explore practical strategies to recognize burnout, challenge common myths, and promote lasting well-being through organizational, team-based, and individual approaches.
The Mayo Clinic Parasitology Workshop offers an immersive learning experience focused on practical skills for parasite identification. This two-day program combines expert-led presentations with hands-on laboratory sessions to help participants apply diagnostic techniques with confidence. Reserve your spot today.
This microlearning provides a practical, structured approach to evaluating specimens for molecular testing using real examples and criteria drawn from laboratory practice to support confident, consistent decision-making.
Mayo Clinic Laboratories is applying AI where it helps most today, strengthening daily workflows while keeping experts firmly in control. From faster specimen intake and triage to data‑informed scheduling, first‑pass support for complex analyses, draft interpretive reporting, and reliable digital pathology quantification, teams use AI to organize information, reduce repetitive steps, and improve consistency. Human‑in‑the‑loop oversight, fit‑for‑workflow design, and regulatory‑aware communication keep the focus on safe, practical gains that benefit patients, clinicians, and laboratorians.