Setting the global standard of diagnostic care
At Mayo Clinic Laboratories, we believe all patients deserve access to world-class diagnostic care. We work with hospitals and healthcare providers around the world to deliver unparalleled expertise and innovative diagnostic evaluations that solve the most complicated cases.
Fully integrated with Mayo Clinic and backed by more than 150 years of clinical experience, Mayo Clinic Laboratories was built upon a tradition of knowledge sharing to improve healthcare around the world. When you work with us, you gain access to the world’s most sophisticated test menu, world-renowned experts, and educational opportunities to strengthen your practice, advance knowledge, and improve patient outcomes.
Focused on quality
At Mayo Clinic Laboratories, test development is based on patient need and guided by quality management protocols modeled on standards and guidelines from the Clinical and Laboratory Standards Institute. Our extensive test validation includes a breadth of specimens with rare abnormalities. Our laboratories are CLIA-certified and CAP-accredited, and we participate in U.S. and international proficiency programs.
Commitment to education
The exchange of knowledge is a founding principle of Mayo Clinic. In this tradition, we provide a wide range of educational offerings to help our clients increase understanding.
- Regionally based clinical specialists guide best practices through physician education.
- Access to Mayo Clinic Laboratories education and insight articles.
- Many courses offer CME credits.
- Online trainings are available, such as “Dangerous Goods Shipping,” with printable certificates.
Enhanced patient outcomes
Mayo Clinic Laboratories is dedicated to the health and well-being of our patients, which means helping providers deliver care in their local settings through the utilization of our comprehensive subspecialty test menu. Our mission is grounded in our belief that the patient’s needs are paramount, and our clients receive access to:
- Expert-developed algorithms that ensure the right patient receives the right test.
- Testing for rare and complex conditions, with some of that testing exclusive to Mayo Clinic Laboratories.
- Expeditious results due to continuous test processing.
“We treat all of the specimens we receive with the same high degree of care and quality, regardless of where the sample is coming from. We could be testing a sample from a patient that lives in Rochester, Minnesota, or from someone that lives halfway across the world.”
Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory

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In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, discuss troublesome organisms making headlines.
Joshua Bornhorst, Ph.D., associate director of Mayo Clinic's Clinical Immunoassay Lab, explains how humans can develop an allergy to the alpha-gal molecule, and he describes a new allergen antibody test that can be used to detect it. Dr. Bornhorst also reviews other tests that should be used in conjunction with alpha-gal testing to accurately identify the scope and underlying cause of the allergy.
In October 2020, Mayo Clinic Laboratories announced two new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Flu season is just now unfolding. But this time, it’s piggy-backed with a pandemic, which threatens to spike with the colder weather as people huddle indoors. Adding to this conundrum is the unsettling fact that, for both COVID-19 and the flu, the symptoms overlap.
In September 2020, Mayo Clinic Laboratories announced one new test along with numerous reference value changes, obsolete tests, and algorithm changes.
In August 2020, Mayo Clinic Laboratories announced five new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
The results are part of a comprehensive study of 16,175 cases performed at Mayo Clinic over an 11-year period.
One of the biggest misunderstandings about genetic testing is a perception that once a variant is identified and analyzed thoroughly, using all the best tools available, it can be associated with a specific disease or condition. But many mutations are deemed “variants of unknown significance,” meaning there is no reported (or insufficient) evidence as to whether or not they cause disease.
Due to the Labor Day holiday (recognized on Monday, September 7), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered. To ensure that your specimen vitality and turnaround times are not affected.
Horatiu Olteanu, M.D., Ph.D., gives an overview of the new T-cell receptor (TCR) β-chain constant region (TRBC1) flow cytometry marker, which is now included in Mayo Clinic Laboratories' routine diagnostic T-cell flow cytometry panel. He discusses when this testing should be ordered, how the addition of TCRBC1 compares to previous testing approaches, and how this marker can assist ordering physicians.
In the last decade or so, genetic testing has evolved from single-gene Sanger based assays to much more complex next-generation sequencing (NGS) based assays. This incredible technology has facilitated the rapid and high-throughput evaluation of many genes (hundreds of thousands of DNA strands) all at once.
In June 2020, Mayo Clinic Laboratories announced three new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted opioid screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of patients who are prescribed opioid pain-relieving medication.