Autoimmune encephalopathy
Autoimmune encephalopathy
is increasingly recognized
Many cases of encephalopathy previously considered infectious are now recognized to have an autoimmune cause. In fact, based on a recent Mayo Clinic study, autoimmune encephalitis was found to be as common as infectious encephalitis.1
KLHL11
Learn more about the world’s first evidence-based test to confirm the presence of Kelch-like protein 11 (KLHL11) autoantibodies.
Ma2-directed illness
Mayo Clinic Laboratories has optimized detection of Ma2-associated autoimmune encephalitis through development of an innovative, enzyme-linked immunosorbent assay.
When to consider testing
Consider autoimmune testing for patients presenting with new-onset encephalopathy (non-infectious or metabolic) and one or more of the following:
Key testing
Phenotypic evaluations
Our autoimmune encephalopathy evaluation is part of an evolving approach to testing for autoimmune neurological disorders using phenotypic-specific evaluations that include multiple antibodies known for their disease association.
Beyond the Test Result
Greg Widseth was suddenly hit by a rare disease that prompted his immune system to attack his brain cells, resulting in as many as 60 seizures a day. Special blood and spinal fluid tests developed by Mayo Clinic Laboratories confirmed that Widseth had antibodies known to target certain brain cells.
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