Immunotherapies have recently emerged as a therapeutic option for patients with non-small cell lung cancer (NSCLC). Therapies have been approved for both first- and second-line treatments of NSCLC tumors with specific patterns of PD-L1 expression.
Immunotherapy test menu
Mayo Clinic Laboratories offers four PD-L1 clones for assessing patient response to specific therapies. The specific PD-L1 clone, scoring method, and eligibility requirements depend on the tumor type, stage of malignancy, previous treatment outcomes, and specific PD-L1 inhibitor under consideration.
The FDA List of Cleared or Approved Companion Diagnostic Devices is frequently updated and provides current guidance for treatment indications and scoring.
Key testing