Mayo Clinic Laboratories > Pathology

Elevating diagnosis through unparalleled expertise

Mayo Clinic has the most robust laboratory and pathology practice for cancer care in the world, offering testing that spans diagnostic, theranostic, and prognostic approaches. Integrated teams of Mayo Clinic pathologists provide expertise for every type and stage of cancer. Our consultative practice strives to provide the highest quality of diagnostic pathology, utilizing only ancillary testing that supports diagnosis in a cost-effective, expedient manner.

Leveraging the Laboratory Pathologists’ Important Roles in Community Medicine
Answers from the Lab Assay identifies patients eligible for new ovarian cancer drug
Eye on Innovation How digital pathology provides faster answers
Patient Spotlight Defying all adds and exploring a remarkable journey beyond diagnosis: Mike Knudson

Pathology Services

Biomarker and companion diagnostic testing Biomarker and companion diagnostic testing
Biomarker and companion diagnostic testing

Browse our suite of diagnostic, therapeutic and prognostic, quantitative and semi-quantitative immunohistochemical stains with interpretation.

Digital imaging Digital imaging
Digital imaging

Our digital imaging services can help providers gain clarity on complex cases. Whether used with immunohistochemistry (IHC) or in situ hybridization (ISH) stains or as part of a specialty renal pathology consultation, our digital imaging services can facilitate a clearer understanding of a patient’s condition.

Digital pathology Digital pathology
Digital pathology

Our digital pathology initiative enhances patient-specimen identification, reduces occurrences of lost or damaged slides, and improves overall patient care. Enabling faster diagnoses, workflow efficiencies, cost savings, and reproduceable results, digital pathology benefits both providers and patients.

Pathology consultation Pathology consultation
Pathology consultation

Completing more than 45,000 consultations each year, we bring unmatched experience to each engagement, providing answers on the most complicated cases. Applying best practices to each consultation, we provide expeditious, evidence-based results.

Primary ciliary dyskinesia Primary ciliary dyskinesia
Primary ciliary dyskinesia

Including both electron microscopy and genetic testing, our primary ciliary dyskinesia assays can provide diagnostic certainty for the rare, genetic disease and facilitate treatments that improve patient outcomes.

Subspecialty testing Subspecialty testing
Subspecialty testing

Offering a vast menu of pathological testing, our subspecialty testing spans the array of pathology. With more than 100 pathologists working in 19 specialized groups, our highly trained pathologists work collaboratively to provide the most comprehensive review of each case.

“DIGITAL PATHOLOGY HAS TRULY REVOLUTIONIZED THE WAY WE PRACTICE. IT HAS ALLOWED ME TO HAVE A QUICKER TURNAROUND TIME ON CONSULTS AND ENHANCED PRODUCTIVITY. AND IT GIVES ME MORE ACCURATE ANNOTATION OF DISTANCE OF THE MARGIN TO THE CANCER AND SIZE OF THE CANCER.”

Miglena Komforti, D.O.

Our difference

Integrated collaboration
Our integration with the clinical practice at Mayo Clinic provides a wealth of insights and experience to guide diagnosis and treatment decisions. Consultation cases may be directed to one pathologist who is an expert in the given area or directed more broadly to the subspecialty group. This collaboration enables information sharing on challenging cases and access to the most up-to-date scientific information and technologies.

Efficient, cost-effective answers
Our clinically driven algorithmic approach helps ensure the right test, for the right patient, at the right time. Our laboratory professionals define and employ comprehensive testing protocols, carefully considering the need for ancillary studies. This ensures high-quality laboratory testing that uses efficient, cost-effective methods and results in reduced laboratory spending.

Commitment to quality
Our testing employs quality management protocols that exceed the minimum requirements established by the Clinical and Laboratory Standards Institute. This ensures our testing processes, instruments, and operations are calibrated optimally. We also apply stringent protocols to specimen collection, storage, and transportation to help safeguard specimen integrity.

News and updates

The latest

Dr. William Morice provides insights on the evolving technologies in medicine

In a Fierce Healthcare article, Dr. William Morice highlights AI, digital pathology, and mass spectrometry as key advancements revolutionizing healthcare diagnostics and treatment.

Learn more
Dr. William Morice provides insights on the evolving technologies in medicine

In a Fierce Healthcare article, Dr. William Morice highlights AI, digital pathology, and mass spectrometry as key advancements revolutionizing healthcare diagnostics and treatment.

Pathways Case Studies: February 2025

Mayo Clinic laboratory experts share case studies that challenge you to test your knowledge of anatomic and clinical pathology.

Pathways Case Studies: January 2025

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff.

Pathways Case Studies: December 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff.

Pathways Case Studies: November 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff.

Pathways Case Studies: September 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff.

Pathways Case Studies: August 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff

Pathways Case Studies: July 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff.

Pathways Case Studies: June 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff

Pathways Case Studies: May 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff

Pathways Case Studies: April 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff

Pathways Case Studies: March 2024

Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff

View More
Resources
Download Pathology test request form
Delivering specialized testing and consultative support for:
Learn more Biopharma
Learn more Commercial laboratories
Learn more Global healthcare
Learn more Hospitals and health systems

LEARN MORE ABOUT HOW WE CAN BUILD YOUR LAB'S POTENTIAL.

INTERESTED IN LEARNING MORE?

Fill out the form below and one of our specialists will be in touch.