Mayo Clinic Laboratories > Pediatrics > Oncology

Oncology

Patient Spotlight Against the odds: Alex Kraatz

Developed with care for meaningful results 

Mayo Clinic Laboratories understands the urgency felt by families when a child is found to have a malignancy. Access to fast, accurate answers is integral to understanding the nature of the illness and making informed decisions on how best to treat it.

Our pediatric oncology testing was carefully developed by a multidisciplinary team of pediatric oncology experts to provide efficient, actionable answers. Our integration with Mayo Clinic’s pediatric oncology practice and ongoing collaboration with molecular geneticists, neuro-oncologists, sarcoma specialists, and genetic counselors propels the development of patient-focused evaluations optimized to identify valuable diagnostic and therapeutic features of some of the most common pediatric cancers.

Fully aligned with testing recommendations put forth by professional medical societies, our pediatric cancer testing includes detailed reports that clarify diagnostic findings, prognostic markers, and treatment associations.

Test menu

Hereditary cancers Hereditary cancers
Hereditary cancers

Mayo Clinic Laboratories’ pediatric hereditary cancer test offerings include single-gene assays that evaluate specific genes already identified in a parent with a hereditary cancer syndrome.

Neuro-oncology Neuro-oncology
Neuro-oncology

Our pediatric-focused neuro-oncology testing includes both comprehensive MayoComplete next-generation sequencing and chromosomal microarray. Used in combination, these tests provide robust coverage of established and emerging cancer-related gene expression, including mutations, rearrangements, fusions, and copy number variants.

Sarcoma and soft-tissue cancers Sarcoma and soft-tissue cancers
Sarcoma and soft-tissue cancers

Our next-generation sequencing sarcoma fusion panel assesses for fusions described in 39 subtypes of soft tissue, bone, and other mesenchymal tumors. Because fusion events can occur between known or novel gene partners, the panel is designed to provide the most comprehensive analysis by including 124 gene fusion pairs, 274 fusion variants, and novel gene partner detection.

Unparalleled expertise

Developed by and with expertise from Mayo Clinic geneticists, pathologists, and oncologists, our testing is informed by more than 150 years of clinic experience. Our collaboration with the clinical practice at Mayo Clinic drives development of clinically actionable testing that can help start the youngest patients on the correct care path.

Personalized, patient-centric testing

Patients are at the heart of our pediatric oncology test development and the reason we carefully curate our genetic panels to include only actionable genes. Our panels deepen our understanding of diagnosis, prognosis, and treatment options, including the latest targeted immunotherapies.

Advanced diagnostics

Our pediatric oncology testing identifies and evaluates genetic variations, including mutations, rearrangements, fusions, and copy number variations. Next-generation sequencing offers increased sensitivity and improved accuracy, yielding a deeper understanding of the unique genetic features of a patient’s cancer to make informed treatment decisions.

News and updates

The latest

Chromosomal microarray better informs brain tumor diagnosis

Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor analysis compared with other test methods.

Learn more
Chromosomal microarray better informs brain tumor diagnosis

Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor analysis compared with other test methods.

New gene panel enhances brain tumor profiles

Cristiane (Cris) Ida, M.D., explains how Mayo Clinic Laboratories' updated neuro-oncology gene panel provides more clinically relevant information for managing adult and pediatric brain tumors.

Hereditary Oncology Testing [Test in Focus]

Wei Shen, Ph.D., explains Mayo Clinic Laboratories' new expert-backed, hereditary oncology panels, which use next-generation sequencing to identify genetic mutations linked to increased cancer risk. By only including clinically significant genes, the panels provide clarity on diagnosis, prognosis, and treatment approaches.

Hereditary oncology: Molecular testing for solid tumors

In this episode of Lab Medicine Rounds, Sounak Gupta, M.B.B.S., Ph.D., assistant professor of Laboratory Medicine and Pathology at Mayo Clinic, discusses hereditary oncology and the importance of performing molecular testing of solid tumors.

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