Optimize patient outcomes.

Stone disease management

Stone disease has a multifactorial etiology involving heredity, lifestyle, and dietary factors. Changes in lifestyle and diet have contributed to the rise in prevalence. The management of stone disease remains complex due to limited effectiveness of treatment, rate of recurrence, and the associated health care costs.

7 steps to clean and dry kidney stones

For the highest quality results, follow the kidney stone preparation steps laid out in our 7 part video series.

Translating testing into care

To optimize patient care, our kidney stone services will help identify metabolic and physical compositions. Mayo Clinic Laboratories’ comprehensive approach and concise report supports your practice with accurate interpretation to guide clinical decisions.

Proper stone collection guidance

Optimum analysis stems from proper specimen collection. Increase accuracy and improve turnaround time by reviewing our stone collection instructions.

Classify the composition

KIDST | Kidney Stone Analysis

When to order testing?

  • First collected stone to identify renal calculi composition.
  • Subsequent stones depending on the clinical situation.
  • In conjunction with a metabolic evaluation to aid in reducing stone recurrences.

Identify complex risk factors

SUP24 | Supersaturation Profile, 24 Hour, Urine

When to order testing?

  • To identify urinary saturations that increase the risk of specific types of stones. In patients with new or recurrent histories of urinary stones.
  • On patients with known risk factors for stones.
  • When a stone is unavailable for analysis to determine the most likely type.
  • In conjunction with a kidney stone analysis to determine patient-specific risk factors.

Test frequency recommendations:  

  • Order two 24-hour collections to assess risk factors.
  • Repeat testing 4–6 weeks after the start of a treatment plan to determine effectiveness and modify accordingly.
  • Test annually for further evaluation.


Approximately 80% of patients with stone events will have recurrent episodes later in life.

Learn more about how to order these evaluations at your institution.