Hot Topic

Hot Topic

Antibodies to aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) are recently described biomarkers seen in a subset of atypical optic neuritis which have revolutionized our understanding of the condition. In this “Hot Topic,” my colleague, Dr. John Chen, will review these advances and how they impact the clinical care of our patients with optic neuritis.

By MCL Education • June 3, 2019

Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic” will provide an overview of a new test developed by Mayo Clinic Laboratories, which uses next-generation sequencing technology to identify mutations in the genome of CMV that may be associated with antiviral resistance.

By MCL Education • May 13, 2019

In this month’s “Hot Topic,” Julia Lehman, M.D., will discuss a rare and potentially fatal mucocutaneous blistering disease that is often associated with an underlying malignancy, called paraneoplastic pemphigus. She will also discuss the specialized tissue and serum testing that is required to establish the diagnosis.

By MCL Education • April 8, 2019

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for diagnosis and their role in management of hemophilia.

By MCL Education • March 28, 2019

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., will cover the need and evidence behind following the order of draw recommendations for routine blood collection. Specifically, does evidence demonstrate a need to collect serum tubes before either potassium EDTA or citrate tubes?

By Brad Karon, M.D., Ph.D. • February 12, 2019

In this month’s “Hot Topic,” Robin Patel, M.D., discusses how matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry works for bacterial identification, including the strengths and limitations of this technology. She also covers Mayo Clinic’s experience with the technology in the clinical laboratory.

By Robin Patel, M.D. • January 15, 2019

In this month’s “Hot Topic,” a group of clinical laboratory technologists from Mayo Clinic’s Component Laboratory discusses a new tool to help standardize acceptable color variation for plasma products.

By Manish Gandhi, M.D. • December 4, 2018

In this month’s “Hot Topic,” Robin Patel, M.D., will discuss the importance of accurate diagnosis of prosthetic-joint infection and its management, focusing on the pathogenesis, clinical presentation, and definition of arthroplasty failure, as well as discuss diagnostic strategies.

By Robin Patel, M.D. • November 5, 2018

In this month’s “Hot Topic,” Robin Patel, M.D., will discuss the bacteria that cause pertussis, also known as whooping cough. Pertussis is highly contagious and spreads rapidly through families, schools, and hospitals. While adults and children may have relatively mild symptoms, the disease can be deadly for infants and newborns.

By Robin Patel, M.D. • October 1, 2018

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., describes how pseudohyperkalemia has many causes, from collection techniques, processing, and even transport. This presentation focuses on the various preanalytic and analytic causes of pseudohyperkalemia and what you as a phlebotomist can do to prevent it.

By Brad Karon, M.D., Ph.D. • September 10, 2018

In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss diagnostic testing options for patients with suspected neuroinvasive Lyme disease or Lyme neuroborreliosis.

By Elitza Theel, Ph.D. • August 20, 2018

In this month’s “Hot Topic,” Bobbi Pritt, M.D., will talk about the different ticks that commonly bite humans, where they can be found, and how to avoid them.

By Bobbi Pritt, M.D. • August 6, 2018

In this month’s “Hot Topic,” my colleagues, Dr. Katherine Geiersbach and Dr. Beiyun Chen, will provide information about the 2018 Focused Update of the ASCO/CAP guidelines for HER2 testing in breast cancer.

By MCL Education • July 2, 2018