In this month’s “Hot Topic,” D. Jane Hata, Ph.D., provides an overview of the epidemiology of Zika virus, as well as the possible clinical features of disease and the recommended laboratory tests to assist in the diagnosis of Zika virus infection.
In this months “Hot Topic,” Christopher Desens, MLS(ASCP) discusses the preparation of platelet-poor plasma for coagulation testing.
In this “Hot Topic,” Nicole Hoppman, Ph.D., discusses mate-pair sequencing, which is the first clinically available test that can characterize almost any chromosomal rearrangement, helping to establish pathogenicity, and, in a neoplastic setting, assist in diagnosis, prognosis, and identification of optimal therapeutic options.
In this month’s “Hot Topic,” Alicia Algeciras-Schimnich, Ph.D., will provide you with valuable information regarding the utility of the prostate specific antigen test, and how the calculation of a prostate health index, or phi, can help to stratify a patient’s risk for prostate cancer and reduce unnecessary biopsies.
In this month’s “Hot Topic,” Ariela Marshall, M.D., provides an overview of venous thromboembolism in the pregnant population, including its risk factors, treatment, and prevention.
Diabetes mellitus type 1 accounts for most juvenile-onset diabetes. In this “Hot Topic,” Andrew McKeon, M.D., discusses a new diabetes evaluation that is now available to help detect disease, differentiate between diabetes type 1 and type 2, and aid in the risk assessment for future diabetes risk.
In this month’s “Hot Topic,” Dragan Jevremovic, M.D., Ph.D., reviews the diagnostic criteria for multiple myeloma and discusses the laboratory tests, including the use of next-generation sequencing, that can be used to help diagnose and manage patients with this disease.
In this “Hot Topic,” Daniel Visscher, M.D., discusses the Mayo Clinic experience in identifying biopsy specimens that demonstrate mucocele-like lesions of the breast and the associated risk of breast cancer.
Millions of Americans suffer from allergies with peanut allergies being of particular interest. In this “Hot Topic,” Melissa Snyder, Ph.D., discusses the diagnosis of allergic disease and the role of component allergen testing.
In this “Hot Topic,” Roshini Abraham, Ph.D., will the discuss the complexity of diagnosing chronic granulomatous disease (CGD) and the DHR/Dihydrorhodamine (DHR) Flow Cytometric Test, blood assay as the most commonly used assay for diagnosis.
Clostridium difficile is an important cause of health care-associated infections. C. difficile infections (CDI) present with a wide range of symptoms, from diarrhea to toxic megacolon. In this “Hot Topic,” Audrey Schuetz, M.D., covers several methods for diagnosing CDI, including molecular NAATs, EIAs, and culture.
In this “Hot Topic,” Darci Block, Ph.D., will explain how a team from Mayo Clinic evaluated collecting blood from infants using the practice of warming the heel prior to puncture, using venipuncture instead of heel puncture, and infant distress as a result of either heel puncture or venipuncture.
Programmed cell death ligand 1 (PD-L1) is a protein that can be expressed on tumor cells and immune cells. In this “Hot Topic,” Anja Roden, M.D., discusses the role of PD-1 – PD-L1 interaction in the immune system and the challenges of PD-L1 testing.