Research

This week’s research roundup features a study on how abnormal expression of programmed death-1 (PD-1) ligand-1(PD-L1) in cancer cells play a crucial role in cancer immune evasion and progression.

By Samantha Rossi • January 20, 2020

This week’s research roundup features a study the identification of a novel homozygous multi-exon duplication in RYR2 among children with exertion-related unexplained sudden deaths in the Amish community.

By Samantha Rossi • January 13, 2020

This week’s research roundup features a case report on glioblastoma of the cerebellopontine angel and internal auditory canal mimicking a peripheral nerve sheath tumor.

By Samantha Rossi • January 6, 2020

This week’s research roundup features a study on how genomic and phenotypic characterization of a broad panel of patient derived xenografts reflects the diversity of glioblastoma.

By Samantha Rossi • December 30, 2019

This week’s research roundup features a study on how mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma.

By Samantha Rossi • December 23, 2019

This week’s research roundup features a study on light chain Amyloidosis induced inflammatory changes in cardiomyocytes and adipose-derived mesenchymal stromal cells.

By Samantha Rossi • December 16, 2019

This week’s research roundup features the evaluation of monoclonal gammopathy of renal significance.

By Samantha Rossi • December 9, 2019

This week’s research roundup features a study the effects of interatrial shunt on pulmonary vascular function in heart failure with preserved ejection fraction.

By Samantha Rossi • December 2, 2019

This week’s research roundup features a study on amyloidosis in surgically resected atrial appendages and the clinical impact on 345 consecutive cases.

By Samantha Rossi • November 25, 2019

This week’s research roundup features a study on how integration of comprehensive genomic analysis and functional screening of affected molecular pathways inform cancer therapy.

By Samantha Rossi • November 18, 2019

This week’s research roundup features a study on how selective YAP/TAZ inhibition in fibroblasts via dopamine receptor DI agonism reverses fibrosis.

By Samantha Rossi • November 11, 2019

This week’s research roundup features coexistence of myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies in adult and pediatric patients.

By Samantha Rossi • November 4, 2019

This week’s research roundup features a study on inherited pathogenic variants in PALB2 and the associated increased risk of breast and pancreatic cancer.

By Samantha Rossi • October 28, 2019