Next-generation sequencing 

Individualized answers for personalized care

At Mayo Clinic, we recognize that multiple factors, such as history, diagnosis, specimen availability, and prognosis, affect which test a patient receives. Understanding the unique genetic features of a patient’s hematologic malignancy is essential to helping physicians select from an array of treatment options to devise an optimal care plan for each patient. Comprehensive genetic testing is the first step in starting patients down the right path.

Our menu of MayoComplete next-generation sequencing assays includes targeted testing for a growing list of hematologic cancers. Utilizing next-generation sequencing, our MayoComplete testing ensures each patient receives personalized answers to guide their care.


Learn more about our full suite of MayoComplete next-generation sequencing panels for hematologic and oncologic conditions.


Precision testing for individual insights

MayoComplete disease-specific, next-generation sequencing hematology panels provide focused insights on genetic variations found in hematological cancers to optimize treatment outcomes. MayoComplete hematology testing includes both comprehensive and targeted assays.

Targeted panels

MayoComplete disease-specific panels provide focused insights on genetic variations to optimize treatment outcomes. MayoComplete next-generation sequencing includes testing for:

Testing advantages

  • Developed, validated, analyzed, and reported by experts.
  • Guides decisions on optimal treatment options, including targeted immunotherapies.
  • High accuracy and sensitivity.
  • A full menu of complementary microarray, FISH, and IHC testing available, providing full-spectrum testing in one laboratory.

Clear answers, definitive reports

Because testing is complex and selecting the right assay can be challenging, our team of board-certified geneticists and genetic counselors is available to assist with questions related to testing options and results interpretation.

MayoComplete next-generation sequencing includes detailed reports that highlight diagnostic findings, therapeutic associations, availability of on- and off-label therapies, prognostic markers, and existence of applicable clinical trials that enable deeper understanding of the best treatment choices.

Learn more about how to order these tests at your institution.