Testing driven by
Mayo Clinic
practice and research

A patient-centered, value-based approach to testing

Our Special Coagulation Laboratory has been at the forefront of patient-centered and value-based diagnostic laboratory testing, research, and patient management for nearly 90 years. Led by a multidisciplinary team of physicians, the laboratory offers a broad repertoire of coagulation tests covering a wide spectrum of bleeding and thrombosis disorders.

By the numbers


profiles focusing on bleeding and
thrombosis disorders


esoteric coagulation test offerings available outside of the profile testing menu


special coagulation tests performed annually

An algorithmic and cost-effective
way of testing

Coagulation-focused algorithms developed collaboratively among physicians, pathologists, laboratorians, and genetic counselors are available. These algorithms recommend approaches for diagnosis of specific diseases and assist in treatment and monitoring of patient care. In addition, they can guide proper and cost-effective test utilization (e.g., activated protein C resistance testing with reflex to factor V Leiden analysis).

A Test in Focus

Rajiv Pruthi, M.B.B.S., gives an overview of the new coagulation NGS testing. He discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action can be taken due to the results of this testing.

Additional resources

By Alyssa Frank • June 3, 2020
By MCL Education • March 28, 2019
By Michelle Odean • March 12, 2019
By MCL Education • March 12, 2019
By MCL Education • October 30, 2017