Mayo Clinic Laboratories > BioPharma Diagnostics > Testing > Therapeutics

Therapeutics

Delivering results through continuous innovation

From controlled substance monitoring to pharmacogenomics (PGx), therapeutics testing provides meaningful answers across a broad range of areas. BioPharma Diagnostics gives collaborators access to Mayo Clinic Laboratories’ robust therapeutics portfolio, which includes comprehensive controlled substance monitoring and addiction rehabilitation profiles as well as leading-edge alcohol biomarker testing. Developed through evidence-driven clinical innovation and designed to deliver clarity on drug and alcohol use, our testing delivers results that advance understanding and improve outcomes.

To learn more about our testing, view our biopharma-specific test catalog and full test catalog.

Test menu

Full suite of therapeutic testing Full suite of therapeutic testing
Full suite of therapeutic testing

Developed through evidence-driven clinical innovation and designed to deliver clarity on drug and alcohol use, our testing delivers results that advance understanding and improve outcomes.

Addiction rehabilitation Addiction rehabilitation
Addiction rehabilitation 

Our approach to urine drug testing for individuals in need of addiction rehabilitation testing aligns with the American Society of Addiction Medicine’s national consensus statement recommending urine drug testing to identify the presence of prescribed and approved medication taken as part of addiction recovery therapy, as well as illicit substances most commonly abused.

Clinical and forensic toxicology Clinical and forensic toxicology
Clinical and forensic toxicology

Our evaluations align with evidence-based clinical laboratory guidelines and use advanced and emerging technologies, including liquid chromatography tandem mass spectrometry (LC/MS/MS) and gas chromatography mass spectrometry (GS/MS), to deliver accurate, actionable results that clarify substance use for improved outcomes.

Confirmatory testing Confirmatory testing
Confirmatory testing

Our approach to confirmatory testing gives providers the flexibility to perform immunoassays locally while enabling confidence through definitive testing that ensures optimal patient care.

Controlled substance monitoring Controlled substance monitoring
Controlled substance monitoring

We offer the industry’s most comprehensive, evidence-based urine drug testing menu, which was developed to be consistent with practice guidelines and help clinicians identify specific prescription drugs, adulterants, and illicit substances.

Drug class testing Drug class testing
Drug class testing

We offer a complete menu of advanced, expert-developed assays to detect for parent drugs and metabolites of specific drug classes. Including testing for benzodiazepines, opioids, stimulants, marijuana, and ethanol, our assays provide results that clarify and confirm drug use.

Precision therapeutics Precision therapeutics
Precision therapeutics

Precision therapeutics, or the use of PGx testing in conjunction with therapeutic drug monitoring (TDM), has the potential to revolutionize medication selection and prescription monitoring. Our TDM and PGx evaluations increase understanding of an individual’s genetic makeup and personalize dosing decisions.

Result interpretation Result interpretation
Result interpretation

Our recommended approach to urine drug testing takes the guesswork out of results interpretations. Our approach uses a combination of specimen validity testing, immunoassays, and targeted screens with interpretations that enable accurate interpretation of controlled substance monitoring test results.

Therapeutics testing overview

We have access to hundreds of assays to identify and monitor both prescribed and illicit drug use. Our cutting-edge evaluations use advanced and emerging technologies, including liquid chromatography tandem mass spectrometry (LC/MS/MS) and gas chromatography mass spectrometry (GS/MS), to deliver accurate, actionable results that clarify substance use for improved outcomes.

When you partner with Mayo Clinic Laboratories, you extend your network to include some of the world’s leading experts. Mayo Clinic clinicians, laboratorians, and genetic counselors are available to discuss testing options, interpret results, or help with case review and coordination.

Comprehensive disease testing

A collaboration with BioPharma Diagnostics includes access to the therapeutics testing capabilities of Mayo Clinic Laboratories, including:

  • Addiction rehabilitation
  • Alcohol biomarker testing
  • Clinical and forensic technology
  • Confirmatory testing
  • Controlled substance monitoring
  • Drug class testing
  • Precision therapeutics
  • Result interpretation
News and updates

The latest

How Kelly DuBois found help at Mayo Clinic

Kelly DuBois recently joined “Symptomatic: A Medical Mystery Podcast” to explain her health journey with Mayo Clinic. In the episode, Kelly, who faced a series of unexplained health issues over two decades, highlighted the help that Mayo Clinic was able to offer her after being misdiagnosed with acromegaly.

Learn more
Toxicology testing for patient care

In this episode, Paul Jannetto, Ph.D., associate professor of laboratory medicine and pathology and director of the Clinical and Forensic Toxicology Lab, Clinical Mass Spectrometry Lab, and Metals Lab at Mayo Clinic, discusses how his three labs support toxicology testing for patient care.

Improving outcomes through comprehensive controlled substance monitoring

Controlled substance testing options vary in the details they provide about patient drug use, painting an incomplete picture of usage patterns that can hinder accurate prescription monitoring and treatment outcomes. However, a new comprehensive Controlled Substance Monitoring Panel, developed by the Clinical and Forensic Toxicology Laboratory at Mayo Clinic Laboratories, offers in-depth analysis on more than 70 different prescription medications and illicit substances to provide clinicians with details and interpretations on patients’ controlled substance use lacking in other laboratory assays.

New High-Resolution Targeted Opioid Screen: Superior Sensitivity and Specificity to Evaluate Adherence to Prescribed Opioid Therapy

In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted opioid screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of patients who are prescribed opioid pain-relieving medication.

Psychotropic PGx Panel for Drug Treatment Optimization [Test in Focus]

Ann Moyer, M.D., Ph.D. gives an overview of this new test available through Mayo Clinic Laboratories. She discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be taken due to the results of this testing.

Pediatric Phlebotomy with Pain Management: Creating an Optimal Experience

This “Phlebotomy” webinar reviews: Having a medical procedure or a lab draw can be fearful for children. Even if it is their first time or they have had a bad past experience, there are ways to make these procedures easier for children.

The Right Medication for You: Pharmacogenomics Testing at Mayo Clinic

How Your Genes Determine which Medications Work Best for You The drugs available today to treat diseases are powerful agents that work as intended for[...]

Ann Moyer, M.D., Ph.D., Makes a Case for Pharmacogenomics

Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in Rochester, Minnesota, makes a case for pharmacogenomics.

Finding the Balance: Legal Issues Arising from Precision Medicine

By taking into account an individual’s genes, lifestyle, and environment, precision medicine offers the prospect of finding individualized therapies that might ultimately cure diseases such as cancer and diabetes. Yet, as with other technological revolutions, precision medicine’s quest for innovation bumps up against a host of legal issues—for patients as well as laboratories and providers of care.

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