Advanced diagnostics, redefined
As the only hospital reference lab integrated with a world-renowned academic healthcare institution, Mayo Clinic Laboratories fuses diagnostic testing innovation with a 150-year history of patient-focused care. In that tradition, we advocate for delivering care as close to the patient as possible, offering a vast menu of esoteric and advanced assays that complements, rather than competes with, local care delivery.
Our proactive consultative approach helps hospital laboratories uncover their financial potential and improve profitability while keeping patient care as the focus. Through synergistic relationships, we equip lab teams and hospital executives with tailored tools and strategies to expand laboratory capabilities and improve efficiencies. This supports the growth of the lab, and the health system, into new areas of diagnostic care.
“Our business model and our mission are to support the local care of patients. We work with hospitals and hospital laboratories to help them insource testing they should to take care of their patients, and give them access to those more uncommon tests we're developing within our practice.”
William Morice II, M.D., Ph.D., President and CEO, Mayo Clinic Laboratories

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An order-entry, clinical decision support tool developed by physicians and scientists at Froedtert and the Medical College of Wisconsin (MCW) for clinicians within the healthcare system who order autoimmune and paraneoplastic antibody panels has significantly improved test utilization, resulting in a 28% reduction in monthly test volumes of impacted tests.
UofL Health – UofL Hospital physicians and laboratory scientists faced challenges in the ordering of autoimmune and paraneoplastic panels: duplicate orders that add unnecessary cost and omitted test orders that could provide the key to the right diagnosis for patients.
Controlled substance testing options vary in the details they provide about patient drug use, painting an incomplete picture of usage patterns that can hinder accurate prescription monitoring and treatment outcomes. However, a new comprehensive Controlled Substance Monitoring Panel, developed by the Clinical and Forensic Toxicology Laboratory at Mayo Clinic Laboratories, offers in-depth analysis on more than 70 different prescription medications and illicit substances to provide clinicians with details and interpretations on patients’ controlled substance use lacking in other laboratory assays.
Being able to identify SARS-CoV-2 in tissue is key to better understand the virus that causes COVID-19. Now, a first-of-its-kind test that detects SARS-CoV-2 in formalin-fixed, paraffin-embedded tissue is available from Mayo Clinic Laboratories.
Dendritic cells play a crucial role in the body's immune response. Research has shown that too few of these cells in the blood may signal a defect in innate immunity. Up to this point, however, no clinical test has been available to count dendritic cells.
Many laboratory directors come from a technical background, however as healthcare becomes increasingly more complex, it is important to also have a strong financial foundation. An effective outreach leader will be able to consistently quantify revenue, cost and profitability of the outreach program, and communicate relevant data to senior leaders.
April 17, 2020 In this "Ask the Expert" article published in the March, 2020 issue of MedicalLab Management, Jane Hermansen, Manager, Outreach and Network Development, describes the elements necessary[...]
March 19, 2019 To realize its full potential, a laboratory outreach program must be managed as a business—a service line within an organization. Jane Hermansen,[...]
March 18, 2019 Jane Hermansen, Outreach and Network Manager at Mayo Medical Laboratories in Rochester, Minnesota, recently authored an article featured in MedicalLab Management on integrating laboratory[...]