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Mayo Clinic Laboratories > Neurology

PUSHING THE BOUNDARIES OF NEUROLOGY DIAGNOSIS

Mayo Clinic Laboratories is leading an evolution in neurology testing. Propelled by ongoing discoveries of clinically relevant biomarkers, our laboratory scientists integrate research findings into test development and implementation. Collaboration between our labs and the clinical practice at Mayo Clinic supports development of clinically validated testing that delivers actionable answers for patients.

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NEUROLOGY TEST SPECIALTIES

Autoimmune disorders Autoimmune disorders
Autoimmune disorders

Covering the spectrum of autoimmune neurological disorders, our evaluations apply a phenotype-specific approach to diagnose and guide treatment for patients affected by immune-mediated neurological illness.

Biopharma testing Biopharma testing
Biopharma testing

With 19 subspecialty labs that perform neurology testing, we are at the forefront of research that integrates novel biomarker discoveries into our evaluations. Our menu, including testing for Alzheimer’s disease, dementia, and autoimmune conditions, provides partners with results that move solutions through the development pipeline.

Demyelinating disease Demyelinating disease
demyelinating disease

We offer sensitive and specific testing to diagnose a range of demyelinating diseases, from classic multiple sclerosis (MS) to atypical MS, AQP4/MOG-associated disorders, and spinal cord disorders.

Dementia Dementia
Dementia

Offering the industry’s most sophisticated suite of testing available, including biomarker evaluations, autoimmune panels, testing for rapidly progressive cases, and an innovative combination assay, Mayo Clinic Laboratories is a one-stop laboratory solution for dementia and Alzheimer’s disease testing.

Epilepsy Epilepsy
Epilepsy

We offer testing that identifies genetic and autoimmune causes of epilepsy. With testing developed by neurologists, epileptologists, and geneticists, physicians can determine the causes of epilepsy in their patients and identify potential treatment options.

Movement disorders Movement disorders
Movement disorders

Our comprehensive movement disorder testing includes an autoimmune movement disorders panel that contains the latest newly discovered clinically actionable antibodies. We also offer hereditary movement disorders testing that covers ataxia, Huntington's disease, Parkinson's disease, and more.  

Neurogenetics Neurogenetics
Neurogenetics

A multidisciplinary team of clinical neurology experts, laboratory scientists, and genetic counselors work collaboratively to develop and implement our neurogenetic testing. Covering the full range of neurogenetic illness, our testing is unparalleled in scope and detail and uses an algorithmic and phenotypic approach that ensures the right patient receives the right test at the right time.

Neuromuscular disorders Neuromuscular disorders
Neuromuscular disorders

Our comprehensive menu of precision testing enables physicians to diagnose and manage patients with disorders such as myasthenia gravis, Lambert-Eaton syndrome, immune-mediated necrotizing myopathy, hereditary myopathy, and more.

Pediatrics Pediatrics
Pediatrics

Including evaluations for autoimmune central nervous system disorders, multiple sclerosis, and narcolepsy, our data-driven pediatric testing provides precision results to guide treatment and place young patients on the path to healing.

Peripheral neuropathy Peripheral neuropathy
Peripheral neuropathy

We offer testing to identify peripheral autoimmune neuropathy with axonal or demyelinating causes, as well as next-generation sequencing to help establish whether a peripheral neuropathy is genetic in nature.

“The ability of Mayo Clinic to make discoveries and translate these into solutions for our patients is critical to our mission.”

John Mills, Ph.D., co-director, Neuroimmunology Laboratory

OUR DIFFERENCE

Clinically driven neurology test menu
Consolidate more of your sendout testing to one trusted lab.

Solving the most complex neurologic cases
We continually innovate to develop new testing approaches that enable answers to the rarest and most complex neurological conditions.

Backed by the world’s leading experts
Our laboratories are led by clinical neurologists who have extensive experience using testing to guide and directly impact patient care. These experts interpret each evaluation, providing clinically actionable answers, not just results.

News and updates

The latest

A Mayo Pathologist’s Journey through Paraneoplastic Syndrome and a Double Lung Transplant: Dr. Brad Karon

After mysterious neurological symptoms began in 2010, Brad Karon, M.D., Ph.D., was diagnosed with paraneoplastic syndrome, a rare condition that led to groundbreaking research and test development at Mayo Clinic. Years later, pulmonary fibrosis and a double lung transplant would test him once again — and redefine his resilience.

Learn more
Hereditary Peripheral Neuropathies Testing [Algorithm]

The algorithm can be viewed here.

Beyond the Test Result: Greg Widseth

Greg Widseth was suddenly hit by a rare disease that prompted his immune system to attack his brain cells, resulting in as many as 60 seizures a day. Special blood and spinal fluid tests developed by Mayo Medical Laboratories confirmed that Widseth had antibodies known to target certain brain cells.

Resources
Download Neurology test request form
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