Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 1

By Kelley Luedke • October 1, 2018

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Carcinoid Heart Disease in Patients with Bronchopulmonary Carcinoid

The prevalence of carcinoid heart disease (CaHD) in bronchopulmonary carcinoid and its relationship with left-sided valvular disease are unknown. All patients with a pathologic diagnosis of bronchopulmonary carcinoid and echocardiography performed at our institution between 2001 and 2016 were retrospectively reviewed. Echocardiograms were reviewed for features of CaHD including valvular leaflet thickening and retraction with resulting regurgitation and/or stenosis. CaHD occurs in less than 1% of patients with bronchopulmonary carcinoid. Bronchopulmonary carcinoid was associated with neither CaHD in the absence of liver metastases nor left-sided valve involvement in the absence of patent foramen ovale. The study was published in the Journal of Thoracic Oncology.

Published to PubMed This Week

• • • • • Applying Standard Clinical Chemistry Assay Validation to Droplet Digital PCR Quantitative Liquid Biopsy Testing
          Clinical Chemistry
        • A Contemporary Review of Male Breast Cancer: Current Evidence and Unanswered Questions
          Cancer and Metastasis Reviews
        • Understanding Biofilms and Novel Approaches to the Diagnosis, Prevention, and Treatment of Medical Device-Associated Infections
          American Journal of Surgical Pathology
        • Decreased Survival and Increased Rate of Fibrotic Progression in Essential Thrombocythemia Chronicled After the FDA Approval Date of Anagrelide
          American Journal Of Hematology
        • New Transgenic NIS Reporter Rats for longitudinal Tracking of Fibrogenesis by High-Resolution Imaging
          Science Reports
        • The Brief Case: A 10-Year-Old Girl with Meningoencephalitis
          Journal of Clinical Microbiology
        • Pediatric Laryngeal Expression and Surgical Treatment of IgG4-Related Disease
          JAMA Otolaryngology–Head & Neck Surgery
        • Techniques for Preemptive Analgesia in Gynecologic Surgery
          Journal of Minimally Invasive Gynecology

Kelley Luedke

Kelley Luedke is a Marketing Channel Manager at Mayo Clinic Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her kitty, and exploring new foods.