| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing | |
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing | |
A 72-year-old man with a history of chronic atrial fibrillation on warfarin anticoagulation and a questionable history of immune-mediated heparin-induced thrombocytopenia was admitted for elective abdominal surgery. His warfarin anticoagulation was bridged with argatroban in the peri-operative period. Two days after the procedure, a DIC/ICF profile was ordered due to a fall in platelet count and hematocrit and operative site oozing. The results of the coagulation laboratory studies are shown below.
| Test | Result | Units | Reference Range |
| Prothrombin time (PT) | 25.1 | sec | 10.3 – 12.8 |
| PT 1:1 mix | 14.5 | sec | 10.3 – 12.8 |
| Activated partial thromboplastin time (APTT) | 58 | sec | 26 - 36 |
| APTT 1:1 mix | 50 | sec | 26 - 36 |
| Dilute Russell viper venom time (DRVVT) screen ratio | 2.3 | ratio | 0.0 – 1.1 |
| DRVVT mix ratio | 2.0 | ratio | 0.0 – 1.1 |
| DRVVT confirm ratio | 0.9 | ratio | 0.0 – 1.1 |
| Thrombin time (TT) | 276 | sec | 15 - 23 |
| Reptilase time (RT) | 17 | sec | 14.0 – 23.9 |
| Clauss fibrinogen | 125 | mg/dL | 200 – 430 |
| PT-derived fibrinogen | 480 | mg/dL | 261 - 595 |
| D-dimer | 750 | D-dimer units (DDU) | 0 - 250 |
| Soluble fibrin monomer complexes (SFMC) | <8 | mcg/mL | 0.0 – 7.9 |
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Jansen Seheult, M.B., B.Ch., B.A.O. Resident, Special Coagulation Mayo Clinic |
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Nahla Heikal, M.D. Senior Associate Consultant, Hematopathology Mayo Clinic |
