June 2019 — Clinical Pathology

A 13-month-old female underwent an allogeneic liver transplant at 3-months of age for end stage liver failure secondary to gestational allo-immune liver disease. Eight months following the transplant, the patient was found to have elevated liver transaminases, hyperbilirubinemia, leukocytosis along with itching and worsening skin rash indicating allograft rejection. Susequent liver biopsies displayed cholestasis features and ductopenic chronic rejection. Measured total serum cholesterol was found to be elevated at 1006 mg/dL. Clinical service then requested a complete lipid profile metabolic analysis.

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Abdulrahman Saadalla, M.B., B.Ch.
Resident, Clinical Pathology
Mayo Clinic
Leslie Donato, Ph.D.
Consultant, Clinical Core Laboratory Services
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine
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