July 2019 — Hematopathology

A seven-year-old female presents with a left cheek mass. Flow cytometric immunophenotyping showed an abnormal cell population that expressed CD2, CD4 (partial weak), CD7, CD38, CD45 (dim), CD56, CD11c, HLA-DR, and TdT. Representative images of the biopsy are shown. Immunohistochemical stains demonstrated the infiltrate was positive for CD123, TCL1A, and TdT. CD1a, CD3, CD20, MPO, and EBER were negative.

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Photo of Joanna Dalland, M.D. Joanna Dalland, M.D.
Fellow, Hematopathology
Mayo Clinic
Photo of Matthew (Matt) Howard, M.D. Matthew (Matt) Howard, M.D.
Consultant, Hematopathology
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine

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