A seven-year-old female presents with a left cheek mass. Flow cytometric immunophenotyping showed an abnormal cell population that expressed CD2, CD4 (partial weak), CD7, CD38, CD45 (dim), CD56, CD11c, HLA-DR, and TdT. Representative images of the biopsy are shown. Immunohistochemical stains demonstrated the infiltrate was positive for CD123, TCL1A, and TdT. CD1a, CD3, CD20, MPO, and EBER were negative.
|Joanna Dalland, M.D.
|Matthew (Matt) Howard, M.D.
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine