August 2019 — Infectious Disease

A 50-year-old man with a past medical history of rheumatoid arthritis (treated with immunosuppressive biologic agents) presented to the Emergency Department with splenomegaly, fevers, thrombocytopenia (platelets 31 x 109/L). After admission, the patient was noted to have decreased fibrinogen, elevated transaminases and total bilirubin, and a ferritin level of 51,000 mcg/L. The patient’s clinical status worsened, necessitating intensive care. A bone marrow biopsy was performed to evaluate the patient’s condition.

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Photo of Andrew P. Norgan, M.D., Ph.D. Andrew Norgan, M.D., Ph.D.
Mayo Clinic Scholar
Instructor in Laboratory Medicine and Pathology
Mayo Clinic
Image of Bobbi Pritt, M.D. Bobbi Pritt, M.D.
Consultant, Clinical Microbiology
Mayo Clinic
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine

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