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September 2019 — Gastroenterology

A 33-year-old female presents to her care team with liver cirrhosis (stage IV) and worsening liver failure. She is well known to her medical team and has a long history of blistering skin lesions in direct light. She received a liver transplant for her condition. The photomicrographs provided are of this patient’s explanted liver.

1) H&E low power magnification of explanted liver with cirrhotic nodules.

2) H&E low power magnification of liver parenchyma with coarse pigment deposition.

3) H&E high power magnification of liver parenchyma with coarse pigment depositon.

4) H&E high power magnification (polarized) of liver parenchyma with coarse pigment deposition.

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Elise Venable, M.B.B.S.
Resident, Anatomic and Clinical Pathology
Mayo Clinic
@VenableMBBS
Tsung-Teh Wu, M.D., Ph.D.
Consultant, Anatomic Pathology
Mayo Clinic
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science

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This post was developed by our Education and Technical Publications Team.