A 68-year-old male with history of chronic lymphocytic leukemia presented with subnephrotic range proteinuria (protein/creatinine ratio of 2.5), hemoglobin (13.1 g/dl) and ESR of 50 mm/hour. Core needle biopsy was performed to assess his proteinuria. Representative images of the biopsy are shown. Immunohistochemistry staining was performed and showed positive CD 20, CD 5, and CD 23.
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|Mazen Osman, M.B., B.Ch.
Resident, Anatomic and Clinical Pathology
|Joseph Grande, M.D., Ph.D.
Consultant, Anatomic Pathology
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science